• Henry E. Jones
  • William M. Artis
Part of the Comprehensive Immunology book series (COMIMUN, volume 7)


Most cutaneous mycotic infections are caused by a group of filamentous fungi known collectively as dermatophytes. There are three dermatophyte genera, Trichophyton, Microsporum,and Epidermophyton The very large number of species in these genera account for more than half of all the fungi causing disease in man.


Stratum Corneum Tinea Capitis Tinea Pedis Tinea Corporis Trichophyton Mentagrophytes 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Aravysky, A. N., 1959, Rare mycological findings in pathological material, Mycopathol. Mycol. Appl 11: 143–154.CrossRefGoogle Scholar
  2. Aravysky, A. N., 1961, Rare mycological findings in pathological material, Mycopathol. Mycol. Appl 16: 177–193.CrossRefGoogle Scholar
  3. Aravysky, A. N., 1964, Rare mycological findings in pathological material. Third communication rare findings in generalized trichophytosis, Mycopathol. Mycol. Appl 22: 185–200.PubMedCrossRefGoogle Scholar
  4. Artis, W. M., and Jones, H. E., 1976, The effect of a mammalian-cell active lymphokine of fungal growth, Fed. Proc 35 (3): 2120.Google Scholar
  5. Basarab, O., How, M. J., and Cruickshank, C. N. D., 1968, Immunological relationships between glycopeptides of Microsporum canis, Trichophyton mentagrophytes and other fungi, Sabouraudia 6: 119–126.PubMedCrossRefGoogle Scholar
  6. Berk, S. H., Penneys, N. S., and Weinstein, G. D., 1976, Epidermal activity in annular dermatophytosis, Arch. Dermatol 112: 485–488.PubMedCrossRefGoogle Scholar
  7. Blank, H., Sagami, S., Boyd, C., and Roth, F. J., 1959, The pathogenesis of superficial fungous infections in cultured human skin, Arch. Dermatol 79: 524–535.CrossRefGoogle Scholar
  8. Bourne, H. R., Lichtenstein, L. M., Melmon, K. L., Henney, C. S., Weinstein, Y., and Shearer, G. M., 1974, Modulation of inflammation and immunity by cyclic AMP, Science 184: 19–28.PubMedCrossRefGoogle Scholar
  9. Cruickshank, C. N. D., Trotter, M. D., and Wood, S. R., 1960, Studies on trichophytin sensitivity, J. Invest. Dermatol 35: 219–223.PubMedGoogle Scholar
  10. Eleuterio, M. K., Grappel, S. F., Caustic, C. A., and Blank, F., 1973, Role of keratinases in dermatophytosis. III. Demonstration of delayed hypersensitivity to keratinases by the capillary tube migration test, Dermatologica 147: 255–260.PubMedCrossRefGoogle Scholar
  11. Götz, H., and Heitman, H. J., 1%7, Uber in vitro Reaktionen von Lymphozyten in Gegenwart von Trichophytin, Hautarzt 18: 23.Google Scholar
  12. Grappel, S. F., Buscavage, C. A., Blank, F., and Bishop, C. T., 1970, Comparative serological reactivities of twenty-seven polysaccharides from nine species of dermatophytes, Sabouraudia 8: 116–125.PubMedCrossRefGoogle Scholar
  13. Grappel, S. F., Fethière, A., and Blank, F., 1971, Effect of antibodies on growth and structure of Trichophyton mentagrophytes, Sabouraudia 9: 50–55.PubMedCrossRefGoogle Scholar
  14. Grappel, S. F., Bishop, C. T., and Blank, F., 1974, Immunology of dermatophytes and dermatophytosis, Bacterio!. Rev 38: 222–250.Google Scholar
  15. Greenberg, J. H., King, R. D., Krebs, S., and Field, R., 1976, A quantitative dermatophyte infection model in the guinea pig—A parallel to the quantitated human infection model, J. Invest. Dermatol 67: 704–708.PubMedCrossRefGoogle Scholar
  16. Hanifin, J. M., Ray, L. F., and Lobitz, W. C., 1974, Immunological reactivity in dermatophytosis, Br. J. Der-matol 90: 1–8.Google Scholar
  17. Helander, I., 1975, Cell-mediated immunity in dermatophytosis, Academic dissertation, University of Turku, Finland. Hopfer, R. L., Grappel, S. F., and Blank, F., 1975, Antibodies with affinity for epithelial tissue in chronic dermatophytosis, Dermatologica 151: 135–143.CrossRefGoogle Scholar
  18. Ito. Y., 1965, On the immunologically-active substances of the dermatophytes. II, J. Invest. Dermatol 45 (4): 285–294.PubMedGoogle Scholar
  19. Jillson, O. F., and Huppert, M., 1949, The immediate wheal and the 24–48 hour tuberculin type edematous reactions to trichophytin, J. Invest. Dermatol 12: 179–185.PubMedGoogle Scholar
  20. Jones, H. E., and Artis, W. M., 1975, Histamine inhibition of human lymphocyte transformation, Clin. Res 23 (3): 452A.Google Scholar
  21. Jones, H. E., Reinhardt, J. H., and Rinaldi, M. G., 1973a, A clinical, mycological, and immunological survey for dermatophytosis, Arch. Dermatol 108: 61–65.PubMedCrossRefGoogle Scholar
  22. Jones, H. E., Rinaldi, M. G., Chai, H., and Kahn, G., 19736, Apparent cross-reactivity of airborne molds and the dermatophytic fungi, J. Allergy Clin. Immunol. 52:346–351.Google Scholar
  23. Jones, H. E., Reinhardt, J. H., and Rinaldi, M. G., 1974a, Acquired immunity to dermatophytes, Arch. Dermatol 109: 840–848.PubMedCrossRefGoogle Scholar
  24. Jones, H. E., Reinhardt, J. H., and Rinaldi, M. G., 19746, Immunologic susceptibilitity to chronic dermatophytosis, Arch. Dermatol 110: 213–220.Google Scholar
  25. Jones, H. E., Reinhardt, J. H., and Rinaldi, M. G., 1974c, Model dermatophytosis in naturally infected subjects, Arch. Dermatol 110: 369–374.PubMedCrossRefGoogle Scholar
  26. Jones, H. E., Reinhardt, J. H., and Greenberg, J., 1974d, Immunologic significance of small (1–10 mm) skin test reactions, J. Invest. Dermatol 62 (5): 544.Google Scholar
  27. Kerbs, S., Greenberg, J., and Jesrani, K., 1977, Temporal correlation of lymphocyte blastogenesis, skin test responses and erythema during dermatophyte infections, Clin. Exp. Immunol 27: 526–530.PubMedGoogle Scholar
  28. Kielstein, P., 1967, Zur Immunobiologie der Rindertrichophytie, Mykosen 10: 205.Google Scholar
  29. Kielstein, P., and Richter, W., 1970, Versuche zur Immunoprophylaxe der Rindertrichophytie, Arch. Exp. Ve-terinaermed 24: 1205–1218.Google Scholar
  30. King, R. D., Khan, H. A., Foye, J. C., Greenberg, J. H., and Jones, H. E., 1975, Transferrin, iron, and dermatophyte inhibitory component definitively identified as unsaturated transferrin, J. Lab. Clin. Med. 86: 204–212.PubMedGoogle Scholar
  31. Longhin, S., and Olaru, V., 1970, The value of immunotherapy in dermatomycoses, in: Proceedings of the Second International Symposium of Medical Mycology, 1967(W. Sowinski, ed.), pp. 181–183Google Scholar
  32. Poznan, Poland. Many, H., Derbes, V. J., and Friedman, L., 1960, Trichophyton rubrum: Exposure and infection within household groups, Arch. Dermatol 82: 226–229.Google Scholar
  33. Monroe, E. W., Wade, T. R., Artis, W. M., Young, J. C., and Jones, H. E., 1976, The transition metal content of human plantar stratum corneum, Clin. Res 25 (3): 284A.Google Scholar
  34. Neisser, A., 1902, Plato’s Versuche über die Herstellung and Verwendung von “Trichophytin,” Arch. Dermatol. Syph. 60: 63–76.Google Scholar
  35. Ottaviano, P. J., Jones, H. E., Jaeger, J., King, R. D., and Bibel, D., 1974, Trichophytin extraction: Biological comparison of trichophytin extracted from Trichophyton mentagrophytes grown in a complex medium and a defined medium, Appl. Microbial 28: 271–275.Google Scholar
  36. Pearsall, N. N., Sundsmo, J. S., and Weiser, R. S., 1973, Lymphokine toxicity for yeast cells, J. Immunol 110: 1444–1446.PubMedGoogle Scholar
  37. Peck, S. M., Osserman, K. E., and Rule, A. H., 1972, Intercellular antibodies: Presence in a Trichophyton rubrum infection, J. Invest. Dermatol 58: 133–138.PubMedCrossRefGoogle Scholar
  38. Ray, T. L., and Wuepper, K. D., 1976, Activation of the alternative (properdin) pathway of complement by Candida albicans and related species, J. Invest. Dermatol 67: 700–703.PubMedCrossRefGoogle Scholar
  39. Sohnle, P. G., and Kirkpatrick, C. H., 1978, Epidermal proliferation in the defense against experimental cutaneous candidiasis, Invest. Dermatol 70: 130–133.CrossRefGoogle Scholar
  40. Sorensen, G. W., and Jones, H. E., 1976, Immediate and delayed hypersensitivity in chronic dermatophytosis, Arch. Dermatol 112: 40–42.PubMedCrossRefGoogle Scholar
  41. Walters, B. A. J., Chick, J. E. D., and Halliday, W. J., 1974, Cell-mediated immunity and serum blocking factors in patients with chronic dermatophytic infections, Int. Arch. Allergy Apply. Immunol 46: 849–857.CrossRefGoogle Scholar
  42. Yu, R. J., Grappel, S. F., and Blank, F., 1972, Inhibition of keratinases by a 2-macroglobulin, Experientia 28: 886.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • Henry E. Jones
    • 1
  • William M. Artis
    • 1
  1. 1.Department of DermatologyEmory UniversityAtlantaUSA

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