Repair, Mutation and Recombination in Bacteria
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When bacterial cells are irradiated with ultraviolet radiation at 254 nm, dimers are formed between adjacent pyrimidines in the same strand of a DNA duplex. The biochemical and genetic study of how the cell deals with this damage has provided a fascinating insight into the genes and proteins involved in replicating, repairing and recombining DNA molecules. It has also provided some indication as to how ultraviolet-induced mutation can occur.
KeywordsExcision Repair Single Strand recA Protein Bacterial Chromosome Phage Recombination
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