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Antibiotic Resistance Determinants of Clostridium perfringens

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Book cover Genetics and Molecular Biology of Anaerobic Bacteria

Part of the book series: Brock/Springer Series in Contemporary Bioscience ((BROCK/SPRINGER))

Abstract

Clostridium perfringens is an anerobic microorganism that forms heat-resistant endospores in the gastrointestinal tract but does not sporulate in most routine culture media. In rich media it grows rapidly and ferments sugars to produce H2 and CO2, the evolution of which helps to maintain an anerobic environment. The organism is aerotolerant; it is capable of surviving for extended periods of time in the presence of O2. C. perfringens is of considerable clinical significance as the causative agent of human clostridial myonecrosis (gas gangrene), food poisoning, necrotic enteritis, and a variety of gastrointestinal diseases in domestic animals. The majority of these syndromes are mediated via the production of extracellular protein toxins (Hatheway, 1990).

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Authors
  1. Julian I. Rood
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Editors and Affiliations

  1. Unité des Anaérobies, Institut Pasteur, 75724, Paris, France

    Madaleine Sebald

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Rood, J.I. (1993). Antibiotic Resistance Determinants of Clostridium perfringens . In: Sebald, M. (eds) Genetics and Molecular Biology of Anaerobic Bacteria. Brock/Springer Series in Contemporary Bioscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-7087-5_9

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  • DOI: https://doi.org/10.1007/978-1-4615-7087-5_9

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