Some Factors Affecting Release of Clearing Factor Lipase from Isolated Perfused Rat Heart

  • H. C. Meng
  • E. Aktin
  • M. F. CrassIII
  • M. Ghosal
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 4)


The presence of a lipolytic enzyme has been demonstrated in a variety of tissue preparations of the heart (2–10). This enzyme has been referred to rather indiscriminately as “lipoprotein lipase,” a term which was introduced by Korn (2). According to Korn this lipase was extracted from rat heart acetone powder in an ammonia buffer in the presence of heparin; the enzyme had little activity unless the substrate which was a coconut oil emulsion (Ediol) was “activated” by serum.


Lipase Activity Lipolytic Activity Perfusion Fluid Alloxan Diabetes Buffer Fluid 
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Copyright information

© Plenum Press 1969

Authors and Affiliations

  • H. C. Meng
    • 1
  • E. Aktin
    • 1
  • M. F. CrassIII
    • 1
  • M. Ghosal
    • 1
  1. 1.Department of Physiology, School of MedicineVanderbilt UniversityNashvilleUSA

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