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Studies with 5-(3-Pyridyl)Tetrazole, a Long-Acting Lipolysis Inhibitor

  • J. N. Pereira
  • G. F. Holland
  • F. Hochstein
  • S. Gilgore
  • S. DeFelice
  • R. Pinson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 4)

Abstract

Although the hypocholesteremic effect of nicotinic acid was reported by Altschul et al1. in 1955, general agreement as to its mechanism of action has not been reached. The demonstration that nicotinic acid is a potent lipolysis inhibitor2, capable of markedly reducing the level of plasma free fatty acids (FFA)3, offers a basis for an explanation of its hypocholesteremic effect.

Keywords

Free Fatty Acid Nicotinic Acid Plasma Cholesterol Plasma Free Fatty Acid Plasma Cholesterol Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press 1969

Authors and Affiliations

  • J. N. Pereira
    • 1
  • G. F. Holland
    • 1
  • F. Hochstein
    • 1
  • S. Gilgore
    • 1
  • S. DeFelice
    • 1
  • R. Pinson
    • 1
  1. 1.Medical Research LaboratoriesChas. Pfizer & Co., Inc.GrotonUSA

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