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Genomic Activation in Differentiated Somatic Cells

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Genomic Adaptability in Somatic Cell Specialization

Part of the book series: Developmental Biology ((DEBO,volume 6))

Abstract

The process of cellular differentiation in developing multicellular organisms culminates in the formation of specialized somatic cell types. Once cell types acquire a specific cellular phenotype for performing a specialized function, no further changes usually occur. We call this the stability of the differentiated state. It is now widely accepted that the process and stability of cell specialization are under genetic control. But the frequency and extent to which this genetic control involves irreversible genetic changes among eukaryotic animals remain unanswered.

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Authors and Affiliations

  1. Department of Physiology and Biochemistry, The Medical College of Pennsylvania, Philadelphia, Pennsylvania, 19129, USA

    Marie A. DiBerardino

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  1. Marie A. DiBerardino
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© 1989 Plenum Press, New York

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DiBerardino, M.A. (1989). Genomic Activation in Differentiated Somatic Cells. In: Genomic Adaptability in Somatic Cell Specialization. Developmental Biology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6820-9_8

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  • DOI: https://doi.org/10.1007/978-1-4615-6820-9_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6822-3

  • Online ISBN: 978-1-4615-6820-9

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