Abstract
In recent years, widespread investigations of synthetic polymers available for cardiac valves, circulatory assist devices, artificial kidneys, heart-lung machines, and other devices for use in contact with blood have put a into focus the needs for antithrombogenic materials which would prevent thrombus formation. Despite many works on the development of antithrombogenic materials, it is not yet a perfectly antithrombogenic chemical structure. Blood circulating within the body comes in contact with a foreign surface so that coagulation often occurs within a few minutes.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Nossel, H. L., Rubin, H., Drillings, M. and Hsieh.: J. Clin. Invest. 47:1172, 1968.
Vroman, L.; Effects of hydrophobic surfaces upon blood coagulation. Thromb. Diath. Haemorrh. 10:455,1964.
Oja, P. D., Holmes, G. W., Perkins, H. A. and Love, J.: Specific coagulation factors adsorption as related to functional groups on surfaces. J. Biomed. Mater. Res. 3:165, 1969.
Falb, R.D., Takahashi, M.T., Grode, G.A. and Leninger, R. I.: Studies on the stability and protein adsorption characteristics of heparinized polymer surfaces by radioisotope labeling techniques. J. Biomed. Mater. Res. 1:239, 1967.
Bokros, J. C., Gott, V. L., Lagrange, L.D., Fadali, A. M. and Ramos, M.D.: Heparin sorptivity and blood compatibility of carbon surfaces. 4: 145,1970.
Friedberg, N. M., Zucker, M. B., Grant, R. A., Kim, S. J.: Platelet retention in glass bead columns: Reversal of adenine nucleotide-induced inhibition by apyrase. Fed. Proc. 30: 423, 1971.
Coller, B. S., and Zucker, M. B.: Reversible decrease in platelet retention by glass bead columns (adhesiveness) induced by disturbing the blood. Proc. Soc. Exp. Biol. Med. 136:769,1971.
Zucker, M. B., Rifkin, P. L., Friedberg, N. M., and Goller, B. S.: Mechanisms of platelet function as revealed by the retention of platelets in glass bead columns. Ann. N. Y. Acad. Sci. 201:138,1972.
Bernstein, E. F., Marzee, U., dayman, M.D., Swanson, S., and Johnston, G. G.: Platelet function following surface injury and shear stress: Adhesion, Aggregation, Release and Factor 3 activity. Ann. N. Y. Acad. Sci. 283:138,1977
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Plenum Press, New York
About this chapter
Cite this chapter
Matsumoto, H., Takayama, T., Matsunaga, H. (1984). Functional Effects of Exposure of Blood Coagulation Factors and Platelets to Synthetic Polymers. In: Bailey, W.J., Tsuruta, T. (eds) Contemporary Topics in Polymer Science. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6743-1_15
Download citation
DOI: https://doi.org/10.1007/978-1-4615-6743-1_15
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-6745-5
Online ISBN: 978-1-4615-6743-1
eBook Packages: Springer Book Archive