Abstract
The injection of ovine prolactin intramuscularly in conscious human subjects (Horrobin, Lloyd, Lipton, Burstyn, Durkin, and Muiruri, 1971) or intraperitoneally in conscious rats (Lockett and Nail, 1965) has been shown to produce an antidiuresis and antinatri-uresis which persists for several hours. The duration of the renal response both in the human subjects and in the rats was due partially to the route of prolactin administration. Thus, to define more clearly the time course of the renal response to prolactin we have monitored renal function in rats before and after the intravenous injection of prolactin.
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References
Horrobin, D.F., Lloyd, I.J., Lipton, A., Burstyn, P.G., Durkin, N., and Muiruri, K.L. (1971). Actions of prolactin on human renal function. Lancet ii, 352–354.
Lockett, M.F. and Nail, B. (1965). A comparative study of the renal actions of growth and lactogenic hormones in rats. J. Physiol. 180, 147–156.
Atherton, J.C., Evans, J.A., Green, R., and Thomas, S. (1971). Influence of variations in hydration and in solute excretion on the effects of lysine-vasopressin infusion on urinary and renal composition in the conscious rat. J. Physiol. 213, 311–327.
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© 1977 Plenum Press, New York
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Bond, G.C., Pasley, J.N., Koike, T.I., Llerena, L. (1977). Inhibition of the Renal Response to Intravenous Prolactin by ADH. In: Dellmann, HD., Johnson, J.A., Klachko, D.M. (eds) Comparative Endocrinology of Prolactin. Advances in Experimental Medicine and Biology, vol 80. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6675-5_8
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DOI: https://doi.org/10.1007/978-1-4615-6675-5_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-6677-9
Online ISBN: 978-1-4615-6675-5
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