Management of Infections in Leukemia and Lymphoma

  • Lowell S. Young


Much of the useful clinical information—as well as persisting controversies surrounding the management of infectious problems in the immunocompromised host—has come from studies of patients with leukemias and lymphomas. That these diseases should be the object of great interest is not difficult to fathom: they are rapidly or ultimately fatal if untreated, the magnitude of treatment with cytotoxic and immunosuppressive agents has few parallels in the therapy of any human illness (probably exceeded only by bone marrow transplantation, which is most often employed for leukemia), and the infectious problems are acute, life threatening, and sometimes highly unusual. Infectious problems developing in other types of immunocompromised patients often result from utilization of the same medications and therapeutic strategies initially attempted in patients with hematologic malignancies. At many medical centers, individuals with acute leukemia have the most severe impairment of host-defense mechanisms and represent the prime example of the immunocompromised host.


Herpes Zoster Acute Leukemia Febrile Episode Hodgkin Disease Documented Infection 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Lowell S. Young
    • 1
  1. 1.Kuzell Institute for Arthritis and Infectious Disease, Division of Infectious DiseasesPacific Presbyterian Medical CenterSan FranciscoUSA

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