Abstract
Improved understanding of the chemical aspects of brain function during the last two decades has changed our concepts of a number of neurologic diseases (Snyder, 1984; Harbough, 1985a). Unfortunately, clinical application of this information has been plagued by longstanding problems with drug delivery to the brain. Neurosurgery may have a role to play in previously non-surgical neurologic disease by the ability of neurosurgeons to overcome problems with drug delivery to the brain. Neurotransmitter augmentation by regional infusion of drugs into the central nervous system may open a whole new field of neurosurgical endeavor.
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Harbough, R.E. (1987). Intracranial Cholinergic Drug Infusion in Patients with Alzheimer’s Disease. In: Altman, H.J. (eds) Alzheimer’s Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6414-0_13
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DOI: https://doi.org/10.1007/978-1-4615-6414-0_13
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