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Restenosis and Remodeling: Is the Adventitia Involved?

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Book cover Arterial Remodeling: A Critical Factor in Restenosis

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 198))

Abstract

Vascular remodeling has assumed great importance as a cause of coronary restenosis. Yet understanding of this complex phenomenon is only recently beginning to grow as more data has emerged. In its most fundamental form, remodeling may be defined as any change in vessel diameter (enlargement or constriction) in response to chronic changes in hemodynamic conditions or humoral factors [1]. With atherosclerosis or after vascular intervention, the coronary artery may exhibit three separate remodeling responses 1) compensatory enlargement, 2) absence of compensation or 3) vascular constriction/shrinkage [2]. Each has substantial implications for the artery lumen.

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Authors and Affiliations

  1. Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

    Jean Grégoire, Michael E. Staab, David R. Holmes Jr. & Robert S. Schwartz

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  1. Jean Grégoire
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  2. Michael E. Staab
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  3. David R. Holmes Jr.
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  4. Robert S. Schwartz
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Editors and Affiliations

  1. Necker University, Paris, France

    Antoine Lafont

  2. Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Eric J. Topol

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Grégoire, J., Staab, M.E., Holmes, D.R., Schwartz, R.S. (1997). Restenosis and Remodeling: Is the Adventitia Involved?. In: Lafont, A., Topol, E.J. (eds) Arterial Remodeling: A Critical Factor in Restenosis. Developments in Cardiovascular Medicine, vol 198. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6079-1_9

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  • DOI: https://doi.org/10.1007/978-1-4615-6079-1_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7785-6

  • Online ISBN: 978-1-4615-6079-1

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