Abstract
Developing a new drug is a cost- and time-consuming process. Rational drug design, i.e. the use of comptuational methods for finding or constructing new drugs, is expected to become an important factor in reducing these costs. We present database-oriented methods that support rational drug design by targetting on the processing of the explosively growing information that becomes available from biomolecular methods, in particular genome research. This information opens the way for new, structure-oriented methods in the search of drugs. The article addresses the biological expert who is interested in the application of database management approaches for domain specific information systems.
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Aberer, K., Hemm, K., Hendlich, M. (1997). Data Management for Ligand-Based Drug Design. In: Suhai, S. (eds) Theoretical and Computational Methods in Genome Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5903-0_16
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DOI: https://doi.org/10.1007/978-1-4615-5903-0_16
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