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The Coupling Between Intracellular pH, Ion Transport, and Chemosensory Discharge

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Book cover Frontiers in Arterial Chemoreception

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 410))

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Abstract

The current model of chemoreception in the carotid body (CB) recognizes the glomus cell as the site of transduction of O2, CO2 and [H+] stimuli. In response to hypoxia or acid hypercapnia, glomus cells are expected to release a neurotransmitter which in turn should increase the firing rate of chemosensory discharges. Consequently, the chemosensory discharges recorded from the carotid sinus nerve could be used to monitor the cellular responses of the chemoreceptor cells.

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© 1996 Springer Science+Business Media New York

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Iturriaga, R., Mokashi, A., Lahiri, S. (1996). The Coupling Between Intracellular pH, Ion Transport, and Chemosensory Discharge. In: Zapata, P., Eyzaguirre, C., Torrance, R.W. (eds) Frontiers in Arterial Chemoreception. Advances in Experimental Medicine and Biology, vol 410. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5891-0_25

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  • DOI: https://doi.org/10.1007/978-1-4615-5891-0_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7702-3

  • Online ISBN: 978-1-4615-5891-0

  • eBook Packages: Springer Book Archive

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