Recent Advances in External Electromagnetic Hyperthermia

  • V. Sathiaseelan
  • Bharat B. Mittal
  • Alan J. Fenn
  • Allen Taflove
Part of the Cancer Treatment and Research book series (CTAR, volume 93)


The use of hyperthermia as an adjuvant cancer treatment to irradiation and chemotherapy, even though accepted by many practitioners as beneficial, has yet to be convincingly demonstrated in multicenter randomized phase III clinical trials. Two phase III clinical studies combining irradiation and hyperthermia performed in the United States [1,2] have shown benefit only in small tumors (≤3 cm in diameter). However, recently completed multicenter phase III clinical trials in Europe involving advanced primary or recurrent breast cancer [3], malignant melanoma [4], and inoperable pelvic tumors [5] are showing more positive results. These clinical studies have also reemphasized that there are still many major technical limitations to be overcome for hyperthermia to become routinely applicable and to make a significant impact on clinical outcome.


Electrical Impedance Tomography Specific Absorption Rate Power Deposition Hyperthermia Treatment Regional Hyperthermia 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • V. Sathiaseelan
  • Bharat B. Mittal
  • Alan J. Fenn
  • Allen Taflove

There are no affiliations available

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