Summary
The negative chronotropic and dromotropic properties of adenosine on the sinus and atrioventricular (AV) nodes have been know since 1929 [Drury et al, 1929]. These potent properties and its short half life in vivo have allowed adenosine to establish its place as a unique and invaluable tool for both elucidating the mechanism of cardiac arrhythmias and for treating supraventricular tachycardia.
Keywords
- Ventricular Tachycardia
- Action Potential Duration
- Rest Membrane Potential
- Sinus Node
- Supraventricular Tachycardia
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Slotwiner, D.J., Lerman, B.B. (1998). Adenosine and Cardiac Arrhythmias. In: Burnstock, G., Dobson, J.G., Liang, B.T., Linden, J. (eds) Cardiovascular Biology of Purines. Developments in Cardiovascular Medicine, vol 209. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5603-9_8
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