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Carbohydrate Recognition Systems in Innate Immunity

  • Ten Feizi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 435)

Abstract

Carbohydrate-protein interactions have emerged as important recognition systems in the orchestration of mechanisms of innate immunity1. Unlike the usual situation of receptor-ligand pairs2, a picture is emerging of recognition systems that operate as triads: receptors, ligands and carriers. Here the receptors are lectins3, the ligands are oligosaccharides, and when they are optimally assembled on carriers (proteins or lipids) functional counter-receptors are formed, as depicted in Figure 1.

Keywords

Recognition System Carbohydrate Ligand Sulfated Oligosaccharide Imperial College School Carbohydrate Binding Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Ten Feizi
    • 1
  1. 1.The Glycosciences Laboratory Imperial College School of MedicineNorthwick Park HospitalHarrowUK

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