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The Aspartic Proteinases

An Historical Overview

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Aspartic Proteinases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 436))

Abstract

Research into the aspartic proteinases has had a rich and diverse history. It began with studies of the digestive juices of man and nepenthes using somewhat primitive technologies. It had a renaissance of biochemical characterisation, followed by a classical period when sequences were defined and catalytic activity identified. It is now very much under the influence of the structural school. Thus, in many ways its history parallels that of painting. And like painting it is now thoroughly commercialised, a mixed blessing which nevertheless keeps many of its practioners well above the breadline.

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Authors and Affiliations

  1. Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, UK

    Tom L. Blundell, Kunchur Guruprasad, Armando Albert, Mark Williams, Bancinyane L. Sibanda & Venugopal Dhanaraj

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  1. Tom L. Blundell
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  1. University of Alberta, Edmonton, Alberta, Canada

    Michael N. G. James

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Blundell, T.L., Guruprasad, K., Albert, A., Williams, M., Sibanda, B.L., Dhanaraj, V. (1998). The Aspartic Proteinases. In: James, M.N.G. (eds) Aspartic Proteinases. Advances in Experimental Medicine and Biology, vol 436. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5373-1_1

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