Skip to main content

The Evolution of Membranes for Hemodialysis

  • Chapter

Abstract

Since Willem Kolff, Nils Alwall and other pioneers performed the first regular dialysis treatments on uremic patients in the 1940s, dialysis membranes have been under continual development with respect to improved functionality and biocompatibility. Bulky ‘plate kidneys’ which were used in the early days of clinical hemodialysis have nowadays been replaced by highly optimized disposable membrane devices containing state of the art synthetic hollow fiber membranes in combination with sophisticated volume-balancing dialysis machines.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. G. Lonnemann, J. Flöge, R. Schindler, T. Behme, B. Lenzner, S. Shaldon, and K.M. Koch, 1989, Passage of cytokine E-coli fragments (CEF) through various hemodialysis (HD) membranes, Kidney Int 35:354.

    Google Scholar 

  2. C.A. Dinarello, G. Lonnemann, R. Maxwell, and S. Shaldon, 1987, Ultrafiltration to reject human interleucin-1-inducing substances derived from bacterial cultures, J. Clin. Microbiol 25:1233–1238.

    PubMed  CAS  Google Scholar 

  3. H. Strathmann, and H. Göhl, 1990, Membranes for blood purification: state of the art and new developments, Contrib. Nephrol 78:119–141.

    PubMed  CAS  Google Scholar 

  4. H. Göhl, R. Buck, and H. Strathmann, 1992, Basic features of the polyamide membranes, in: The evolution of a synthetic membrane for renal therapy, Contrib. Nephrol, Volume 96 (S. Shaldon, and K.M. Koch, eds.), pp. 1–25, Karger, Basel.

    Google Scholar 

  5. J. Flöge, C. Granolleras, G. Deschodt, M. Heck, G. Baudin, B. Branger, O. Tournier, B. Reinhard, G.M. Eisenbach, L.C. Smeby, K.M. Koch, and S. Shaldon, 1989, High-flux synthetic versus cellulosic membranes for β2-microglobulin removal during hemodialysis, hemodiafiltration and hemofiltration, Nephrol Dial. Transplant 4:653–657

    Google Scholar 

  6. H. Göhl, C.M. Bell, R. Buck, R. Deppisch, H. Straatman, and M. Pirner, 1992, Visualization and measurement of microdomains in polyamide dialysis membranes: Optimized size facilitates performance and biocompatibility, Blood Purif 10(2):86.

    Google Scholar 

  7. F. Gejyo, S. Odani, T. Yamada, N. Honma, H. Saito, Y. Suzuki, Y. Nakagawa, H. Kobayashi, Y. Maruyama, Y. Hirasawa, M. Suzuki, and M. Arakawa, 1986, β2-microglobulin: A new form of amyloid protein associated with chronic hemodialysis, Kidney Int 30:385–390.

    Article  PubMed  CAS  Google Scholar 

  8. N. Braun, S. Rosenfeld, M. Giolai, W. Banzhaf, R. Fretschner, H. Warth, C. Weinstock, R. Deppisch, C.M. Erley, G. A. Müller, and T. Risler, 1995, Effect of continuous hemodiafiltration on IL-6, TNF-α, C3a, and patients with SIRS/septic shock using two different membranes, in:. Continuous extracorporeal treatment in multiple organ dysfunction syndrome, Contrib. Nephrol, Volume 116 (H.G. Sieberth, H.K. Stummvoll, and H. Kierdorf, eds.), pp. 89–98, Karger, Basel.

    Google Scholar 

  9. E. Klein, F.F. Holland, A. Donnaud, A. Lebeouf, and K. Eberle, 1977, Diffusive and hydraulic permeabilities of commercially available cellulosic hemodialysis films and hollow fibers, J. Membr. Sci 2:349–364.

    Article  CAS  Google Scholar 

  10. S. Zitta, A. Mauric, J. Roob, and H. Hölzer, 1995, Clinical evaluation of polyflux dialyzer membranes, Blood Purif 13:28–29.

    Google Scholar 

  11. R. Deppisch, M. Betz, G.M. Hänsch, E.W. Rauterberg, and E. Ritz, 1992, Biocompatibility of the polyamide membranes, in: The evolution of a synthetic membrane for renal therapy, Contrib. Nephrol, Volume 96 (S. Shaldon, and K.M. Koch, eds.), pp. 26–46, Karger, Basel.

    Google Scholar 

  12. R. Deppisch, E. Ritz, G.M. Hänsch, M. Schöls, and E.W. Rauterberg, 1994, Biocompatibility-perspectives in 1993, Kidney Int 45(S44):77–84.

    Google Scholar 

  13. R. Deppisch, U. Haug, H. Göhl, and E. Ritz, 1994, Role of proteinase/antiproteinase inhibitor disequilibrium in the bioincompatibility induced by artificial surfaces, Nephrol. Dial Transplant 3(suppl): 17–23.

    Google Scholar 

  14. C. Combe, M. Pourtein, V. de Précigout, A. Baquey, D. Morel, L. Potaux, P. Vincendeau, J.H. Bézian, and M. Aparicio, 1994, Granulocyte activation and adhesion molecules during hemodialysis with cuprophane and a high flux biocompatible membrane, Am. J. Kid. Dis 24(3):437–42.

    PubMed  CAS  Google Scholar 

  15. M. Haag-Weber, B. Mai, R. Deppisch, H. Goehl, and W.H. Hoerl, 1994, Studies on biocompatibility of different dialyzer membranes: role of complement system, intracellular calcium and inositol-triphosphate, Clin. Nephrol 41:245–251.

    PubMed  CAS  Google Scholar 

  16. P.R. Craddock, D. Hammerschmidt, J. White, A.P. Dalmasso, and H.S. Jacob, 1977, Complement (C5a)-induced granylocyte aggregation in vitro: a possible mechanism of complement mediated leucostasis and leucopenia, J. Clin. Invest 60:260–263.

    Article  PubMed  CAS  Google Scholar 

  17. L.S. Kaplow, and J.A. Goffinet, 1968, Profound neutropenia during early phase of hemodialysis, J. Am. Med. Ass 203:1135–1137.

    Article  CAS  Google Scholar 

  18. H. Sperschneider, G. Steiner, R. Dietrich, R. Deppisch, and G. Stein, 1997, Reduced thrombogenic activity and heparin consumption in extracorporeal blood purification circuits: in-vivo study with microdomain-modified surfaces, Blood Purif 15(S2):47.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer Science+Business Media New York

About this chapter

Cite this chapter

Storr, M., Deppisch, R., Buck, R., Goehl, H. (1998). The Evolution of Membranes for Hemodialysis. In: Hıncal, A.A., Kaş, H.S. (eds) Biomedical Science and Technology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5349-6_25

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5349-6_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7440-4

  • Online ISBN: 978-1-4615-5349-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics