Abstract
Effective intercellular communication is essential for the proper integration of any multicellular system into a functioning syncytium. In many tissues an intercellular link is provided by arrays of aqueous protein channels known as gap junctions. Individual cells communicate with their neighbours by the exchange of ions and small molecules through gap junctions. In this way a biological signal may be relayed from one cell to a distant neighbour via a chain of cells.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Attwell, D., Wilson, M. & Wu, S. M. (1985): The Effect of Light on the Spread of Signals through the rod network of the Salamander Retina, Brain Research, 343, No. 1, 79–88.
Baigent, S. A., Stark, J. & Warner, A. E. (1997a): Modelling The Effect Of Gap Junction Nonlinearities In Systems of Coupled Cells’. J. theor. Biol., 186, 223–239.
Baigent, S. A., Stark, J. & Warner, A. E. (1997b): The Convergent Dynamics of Two Cells Coupled by a Nonlinear Gap Junction. (Submitted to IMA J. Math. Appl. Med. Biol.).
Brayton, R. K. & Moser, J. K. (1964), A theory of Nonlinear Networks, I,Q. Appl. Math., Vol XXII, No. 1, 1–33.
De Mello, W. C. (1987): Modulation of Junctional Permeability. In: Cell-to-cell communication (ed. Walmor C. de Mello), Plenum Press, New York.
Dongming, C., Winslow, R. L. & Noble, D. (1994): Effects of Gap Junction Conductance on Dynamics of Sinoatrial Node Cells: Two-Cell and Large-Scale Network Models. IEEE Trans. Biomed. Eng., 41, No. 3, 217–231.
Golubitsky, M. & Schaeffer, D. G. Singularities and Groups in Bifurcation Theory, Vol. 1, Springer-Verlag, 1988.
Guthrie, S. C., Turin, L. & Warner, A. E. (1988): Patterns of junctional communication during development of the early amphibian embryo. Development, 103, 769–783.
Iannelli, P., Baigent, S. & Stark, J. (1997): Inertial Manifolds for Dynamics of Cells Coupled by Gap Junctions. (Submitted to Dynamics and Stability of Systems).
MacKay, R. S. (1996). DYNAMICS OF NETWORKS: Features which Persist from the Uncoupled Limit. (Lectures Notes, From Finite to Infinite Dimensional Systems, Newton Institute, Cambridge).
Nagajski, D. K., Guthrie, S. C., Ford, C. C. & Warner, A. E. (1989): The Correlation Between Patterns of Dye Transfer Through Gap Junctions and Future Developmental fate in Xenopus: the Consequences of U. V. Irradiation and Lithium Treatment, Development, 105, 747–752.
Oster, G., Perelson, A. & Katchalsky, A. (1971): Network Thermodynamics, Nature (Loud.) 234, 393–399.
Sakamoto, K. (1990): Invariant manifolds in singular perturbation problems for ordinary differential equations. Proc. Royal Soc. Edin. A, Vol. 116, 45–78.
Warner, A. E., Guthrie, S. C. & Gilula, N. M. (1984): Antibodies to Gap-Junctional Protein Selectively Disrupt Junctional Communication in the Early Amphibian Embryo, Nature, 311, 127–131.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Baigent, S., Stark, J., Warner, A. (1998). Some Aspects of Gap Junction Dynamics in Embryonic Systems. In: Holcombe, M., Paton, R. (eds) Information Processing in Cells and Tissues. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5345-8_2
Download citation
DOI: https://doi.org/10.1007/978-1-4615-5345-8_2
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-7438-1
Online ISBN: 978-1-4615-5345-8
eBook Packages: Springer Book Archive