Abstract
Liver macrophages possess the ability to secrete a wide array of biologically active compounds including cytokines, nitric oxide, oxygen radicals and eicosanoids. Eicosanoid formation has been shown to be elicited by a number of particulate (bacteria, viruses, zymosan, immune complexes) and soluble (phorbol ester, PAF, C3a, fluoride, calcium ionophore, LPS, cytokines) agents. The release of arachidonic acid (AA) and eicosanoids in these cells has been shown to be controlled by glucocorticoids (1), intracellular pH (2), calcium ions (3,4), protein kinase (PK) C (5–7) and albumin in the cell media (8).
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© 1997 Springer Science+Business Media New York
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Ambs, P., Fitzke, E., Dieter, P. (1997). Regulation of Eicosanoid Synthesis in Liver Macrophages. In: Honn, K.V., Nigam, S., Marnett, L.J. (eds) Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2. Advances in Experimental Medicine and Biology, vol 400. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5325-0_12
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DOI: https://doi.org/10.1007/978-1-4615-5325-0_12
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