Effects of Interferential Current in Cellular Systems
Electrotherapy with so-called Interferential Current (IFC) represents a well established type of medical treatment of pain, chronic inflammations and various other diseases (1). IFC is a modulated wave form generated by superposition of 2 alternating currents with slightly different frequencies usually close to 4000 Hz. It is applied via skin electrodes and can readily penetrate into the body. Some of the beneficial effects of IFC are based on direct stimulation of excitable cells. Until now there is not enough knowledge about possibly diverse effects of IFC upon the various types of non-excitable cells in the body.
KeywordsManifold DMSO Psoriasis Sine Toxicology
Unable to display preview. Download preview PDF.
- 1.Nikolova L: Treatment with interferential current. Churchill Livingstone, Edinburgh-London-Melbourne-New York (1987)Google Scholar
- 5.Wobus AM, Kleppisch T, Maltsev V, Hescheler J: Cardiomyocyte-like cells differentiated in vitro from embryonic carcinoma cells P19 are characterized by functional expression of adrenoceptors and Ca 2+ channels. In Vitro Cell. Dev. Biol. 30A: 425–434 (1994)Google Scholar
- 7.Lee Kj, Ross RS, Rockman HA, Harris AN, O’Brien TX, van Bilsen M, Shubeita HE, Kandolf R, Brem G, Price J, Evans SM, Zhu H, Franz WM, Chien KR: Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. J. Biol.Chem. 267: 15875–15885 (1992)PubMedGoogle Scholar
- 10.Gottwald E, Weibezahn KF, Knedlitschek G, Krüger E, Wobus A, Dertinger H: Can extremely low frequency interferential electric fields induce differentiation ? presented at the Bioelectromagnetic Society Meeting, June 7–11, 1998, Florida, USAGoogle Scholar
- 12.Wolf B, Dertinger H, Wolf G: Die Wirkung des Interferenzstrom auf Psoriasis vulgaris. Akt. Dermatol. 22: 94 — 97 (1996)Google Scholar