Aging and Dementia of the Alzheimer type in Persons with Mental Retardation

  • Henryk M. Wisniewski
  • Wayne Silverman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 446)


Aging during the senior years is part of the normal process of life span development. We are born, mature, and if we are fortunate, we grow old before we die. Unfortunately, the process of growing old is associated with declining status in many respects, physical and cognitive. These declines can be related to the concept of reserve: the greater the reserve the longer the organism will be able to avoid any functional deficit. Disease processes, by and large, appear to diminish our reserves. Therefore, in persons suffering from various diseases, age-associated functional impairments are observed earlier and the life span may be shortened.


Mental Retardation Alzheimer Disease Down Syndrome Premature Aging Alzheimer Type 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Henryk M. Wisniewski
    • 1
  • Wayne Silverman
    • 1
  1. 1.Departments of Pathological Neurobiology and PsychologyNew York State Institute for Basic Research in Developmental DisabilitiesStaten IslandUSA

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