The Stimulation of Proliferation of Carcinogenically Initiated INIT/C3H/10T1/2 Cells by Imposing a 60 Hz Magnetic Field: A Magnetic Field or a Thermal Effect?

  • Sek Wen Hui
  • Ya Li Zhao
  • Patricia G. Johnson


Exposure of humans to environmental levels of EMF has been epidemiologically linked with a variety of health risks, including childhood cancers,1 leukemia among electrical workers,2 brain cancer3 and breast cancer.4,5 In addition, EMF influences have been reported in cellular studies, on cell cycle progression,6 calcium oscillations,7 cell proliferation6 and oncogene transcription.8,9 However EMF research has produced as many negative or inconclusive results as positive, from both epidemiology10,11,12 and in vitro cellular research (e.g. calcium uptakel3 and oncogene transcription14,15). Most evidence indicates that EMF does not have mutagenic or genotoxic effects.16,17 However, one line of inquiry concerns the possible cancer promoter or copromoter behavior of EMF, possibly by altering transmembrane signal transduction or intercellular communication.


Calcium Oscillation Mouse Embryo Fibroblast Magnetic Field Exposure Sham Condition Electrical Worker 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Sek Wen Hui
    • 1
  • Ya Li Zhao
    • 1
  • Patricia G. Johnson
    • 1
  1. 1.Membrane Biophysics Laboratory Department of BiophysicsRoswell Park Cancer InstituteBuffaloUSA

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