Skip to main content

Changes of Intercellular Communication Induced by Alternating Electric Fields Correlate with Changes of cAMP

  • Chapter
  • 34 Accesses

Abstract

The role of the cellular membrane as the main site for the interaction with low frequency electric fields has been confirmed by experimental evidence over the last years. Signal transduction processes, mediated by second messengers such as cyclic AMP or Ca, have been shown to be influenced by the interaction of the field with components of the cell membrane e.g. receptor molecules or ion channels1–3.

Keywords

  • Intercellular Communication
  • cAMP Concentration
  • cAMP Content
  • Signal Transduction Process
  • Mouse Fibroblastic Cell Line

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is a preview of subscription content, access via your institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • DOI: 10.1007/978-1-4615-4867-6_104
  • Chapter length: 3 pages
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
eBook
USD   219.00
Price excludes VAT (USA)
  • ISBN: 978-1-4615-4867-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD   279.99
Price excludes VAT (USA)
Hardcover Book
USD   329.99
Price excludes VAT (USA)

References

  1. W. Grundler, F. Kaiser, F. Keimann and J. Walleczek, Mechanisms of electromagnetic interaction with cellular systems. Naturwissenschaften 79: 551–9 (1992)

    ADS  CrossRef  Google Scholar 

  2. G. Knedlitschek, M. Noszvai-Nagy, H. Meyer-Waarden, J. Schimmelpfeng, K.F. Weibezahn and H. Dertinger, Cyclic AMP response in cells exposed to electric fields of different frequencies and intensities. Radiat Environ Biophys 33: 141–7 (1994)

    CrossRef  Google Scholar 

  3. R.P. Liburdy, Calcium signalling in lymphocytes and ELF fields. Evidence for an electric field metric and a site of interaction involving the calcium channel. FEBS 301: 53–9 (1992)

    CrossRef  Google Scholar 

  4. M.V.L. Bennett, L.C. Barrio, T.A. Bargiello, D.C. Spray, E. Hertzberg and J.C. Sáez, Gap Junctions: New tools, new answers, new questions, Neuron, 6: 305–320, 1991

    CrossRef  Google Scholar 

  5. S. Lee, N.B. Gilula and A.E. Warner, Gap junctional communication and compaction during preimplantation stages of mouse development. Cell 51: 851–860, 1987.

    CrossRef  Google Scholar 

  6. M.V.L. Bennett, D.C. Spray and A.L. Harris, Electrical Coupling in Development, Amer. Zool. 21: 413–427, 1981.

    Google Scholar 

  7. W.R. Loewenstein and Y. Kanno, Intercellular Communication and the control of tissue growth: lack of communication between cancer cells, Nature 209: 1248–1289, 1966.

    ADS  CrossRef  Google Scholar 

  8. G.L. Nicolson, K.M. Dulski and J.E. Trosko, Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells, Proc. Natl. Acad. Sci. 85: 473–476, 1988.

    ADS  CrossRef  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and Permissions

Copyright information

© 1999 Springer Science+Business Media New York

About this chapter

Cite this chapter

Weibezahn, K.F., Knedlitschek, G., Sontag, W., Stein, J.C., Gottwald, E., Dertinger, H. (1999). Changes of Intercellular Communication Induced by Alternating Electric Fields Correlate with Changes of cAMP. In: Bersani, F. (eds) Electricity and Magnetism in Biology and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4867-6_104

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-4867-6_104

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7208-0

  • Online ISBN: 978-1-4615-4867-6

  • eBook Packages: Springer Book Archive