Genotoxicity Tests

Application to Occupational Exposure as Biomarkers
  • Ali E. Karakaya
  • Semra Sardas
  • Sema Burgaz
Part of the NATO ASI Series book series (NSSA, volume 302)


Using biomarkers for screening in workers who had known or suspected contact with genotoxic chemicals can be useful in quantifying exposure and assessing genotoxic risk. In this research the genotoxic risk of the following Turkish occupational groups (furniture workers, nurses, operating room personnel, hospital sterilising staff, engine repair workers, road-paving workers, car painting workers and hair colorists) were evaluated. Results of some markers of exposure and cytogenetic biomarkers (sister chromatid exchange, micronucleus assay and comet assay) has been assessed in the above mentioned occupational groups.


Comet Assay Ethylene Oxide Occupational Group Sister Chromatid Exchange Mandelic Acid 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Ali E. Karakaya
    • 1
  • Semra Sardas
    • 1
  • Sema Burgaz
    • 1
  1. 1.Faculty of Pharmacy Department of ToxicologyGazi UniversityHipodromAnkaraTurkey

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