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Oxygen and Ion Concentrations in Normoxic and Hypoxic Brain Cells

  • Chapter
Oxygen Transport to Tissue XX

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 454))

Abstract

The goal of the present contribution is to discuss the relationships among brain oxygen tension, energy (ATP) level, and ion gradients and movements. The function of the CNS, the generation and transmission of impulses, is determined to a large extent by the movements of ions. Hence elucidation of these relationships is necessary to the understanding of how brain works. Moreover, such knowledge is indispensable for the design of rational therapies for treatment of a large group of pathological states caused by lack of oxygen.

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Author information

Authors and Affiliations

  1. Department of Anatomy School of Veterinary Science, University of Bristol, Bristol, BS2 8EJ, UK

    Ian Silver & Maria Erecińska

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  1. Ian Silver
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  2. Maria Erecińska
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Editor information

Editors and Affiliations

  1. Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Antal G. Hudetz

  2. University of Maryland, Baltimore County, Baltimore, Maryland, USA

    Duane F. Bruley

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© 1998 Springer Science+Business Media New York

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Silver, I., Erecińska, M. (1998). Oxygen and Ion Concentrations in Normoxic and Hypoxic Brain Cells. In: Hudetz, A.G., Bruley, D.F. (eds) Oxygen Transport to Tissue XX. Advances in Experimental Medicine and Biology, vol 454. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4863-8_2

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  • DOI: https://doi.org/10.1007/978-1-4615-4863-8_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7206-6

  • Online ISBN: 978-1-4615-4863-8

  • eBook Packages: Springer Book Archive

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