Abstract
The lack of aerobic metabolism during ischemic organ preservation plays a pivotal role in the development of tissue alterations during the storage period and favours the manifestation of reper-fusion injuries, deteriorating organ viability upon postischemic resumption of nutritive blood circu-lation. Gaseous insufflation of oxygen via the venous vascular system has proven to be a useful tool to prevent anoxic tissue injury during extended time periods of ischemic preservation of kidneys (Isselhard et al., 1972) or livers (Minor and Isselhard, 1996; Minor et al., 1996) and to allow for an improved recovery of the persufflated organ after transplantation (Fischer et al., 1978; Minor et al., 1997b; Rolles et al., 1989).
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References
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Minor, T., Vollmar, B., Klauke, H., Isselhard, W., Menger, M.D. (1998). Gaseous Oxygenation of the Ischemic Rat Liver. In: Hudetz, A.G., Bruley, D.F. (eds) Oxygen Transport to Tissue XX. Advances in Experimental Medicine and Biology, vol 454. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4863-8_11
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DOI: https://doi.org/10.1007/978-1-4615-4863-8_11
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