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Transient Synchronization of Propagating Discharges in Neocortical Slices

  • D. Golomb
  • E. Kozhinsky
  • I. A. Fleidervish
  • M. J. Gutnick

Abstract

When cortical GABAA inhibition is blocked, a brief local stimulation above a certain intensity elicits a population discharge. In cortical slices1,2,3, this discharge consists of spatially and temporally localized neuronal activity, which may be viewed as an in vitro experimental model for focal epileptic discharge. The cellular equivalent of this traveling activity is characterized by a depolarization envelope, upon which a train of action potential rides. Studying pulse propagation is expected to uncover the relationship between cortical underlying circuitry and collective dynamical phenomena.

Keywords

Cortical Slice Synaptic Depression Discharge Propagation Synchrony Measure Local Synchrony 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • D. Golomb
    • 1
  • E. Kozhinsky
    • 1
  • I. A. Fleidervish
    • 1
  • M. J. Gutnick
    • 1
  1. 1.Zlotowski Center for Neuroscience and Dept. of PhysiologyBen-Gurion UniversityBeer-ShevaIsrael

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