Advertisement

Disorders of Gastric Motility and Emptying

  • Konrad Schulze-Delrieu

Abstract

Disorders that affect gastric motility and emptying pose a considerable diagnostic and therapeutic challenge; one. has to suspect and demonstrate a disorder, determine its cause and assess its severity, and devise a rational and safe treatment plan. Tests of gastric emptying and motility play a minor role in this process. None provide a comprehensive assessment of the role of the stomach in mechanical digestion.

Keywords

Gastric Emptying Atrophic Gastritis Pernicious Anemia Gastric Motility Early Satiety 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Meyer Jil. Motility of the stomach and gastroduodenal junction. In: Johnson LH, ed. Physiology of the gastrointestinal tract, yet 1, 2nd ed. New York: Raven Press, 1987;613–629.Google Scholar
  2. 2.
    Kelly KA. Effect of gastric surgery on gastric motility and emptying. In: Akkermans LMA, Johnson AG, Read NW, eds. Gastric and gastroduodenal motility. New York: Praeger, 1984:241–262.Google Scholar
  3. 3.
    Poitras P, Picard M, Dery R,Giguere A,Picard D,Morais J,Plourde V,Boivin M. Evaluation of gastric emptying function in clinical practice. Digestive Diseases & Sciences. 1997; 42(11):2183--9.CrossRefGoogle Scholar
  4. 4.
    Read NW, Houghton LA. Physiology of gastric emptying and pathophysiology of gastroparesis. Gastroenterology Clinics North Am 1989; l8(2);359–373.Google Scholar
  5. 5.
    Quigley EM. Gastric and small intestinal motility in health and disease. Gastroenterology Clinics of North America. 1996; 25(l):113–45.PubMedCrossRefGoogle Scholar
  6. 6.
    Stadaas J, Aune S. Intragastric pressure/volume relationship before and after vagotomy. Acta Chir Scand 1970;136:611 615.Google Scholar
  7. 7.
    Grundy D, Hutson D, Scratcherd T. A permissive role of the vagus nerve in the genesis of corporto-antral reflexes in the anaesthetized ferret. J Phvsiol 1986;381:377–384.Google Scholar
  8. 8.
    Lu CH, and Schulze-Delrieu K. Pyloric deformation from peptic disease. Evidence for incompetence rather than obstruction. Dig Dis Sci 1990;35:1459–1467.PubMedCrossRefGoogle Scholar
  9. 9.
    Bromster D. Gastric emptying rate in gastric and duodenal ulceration: a clinical study including the changes of the gastric contents after a liquid test meal. Scand J Gastroenterol 1969;4:193–201.PubMedCrossRefGoogle Scholar
  10. 10.
    Tatsuta M, Oishi H, Okuda S. Gastric emptying in patients with fundal gastritis and gastric cancer. Gut 1990;31:767–769.PubMedCrossRefGoogle Scholar
  11. 11.
    Davies WT, Kirkpatrick JR, Owen GM, Shields R. Gastric emptying in atrophic gastritis and carcinoma of the stomach. Scand J Gastroenterol 1971;6:297–301.PubMedCrossRefGoogle Scholar
  12. 12.
    Halvorsen L, Dotevall G, Walan A. Gastric emptying in patients with achlorhydria or hyposecretion of hydrochloric acid. Scand J Gastroenterol 1973;8:395–399.PubMedGoogle Scholar
  13. 13.
    Miller LJ, Malagelada JR, Longstreth GF, Go VL. Dysfunctions of the stomach with gastric ulceration. Dig Dis Sci 1980; 11: 857–864.CrossRefGoogle Scholar
  14. 14.
    Dubois A, Van Erdewegh P, Gardner JD. Gastric emptying and secretion in Zollinger Ellison syndrome. J Clin Invest 1977;59:255–263.PubMedCrossRefGoogle Scholar
  15. 15.
    Meyer JH, Ohaski H, Jehn D, Thompson JB. Size of liver particles emptied from the human stomach. Gastroenterology 1981;80:1489–1496.PubMedGoogle Scholar
  16. 16.
    Sarna SK, Daniel EE. Vagal control of gastric electrical control activity and motility. Gastroenterology 1975;68:301–308.PubMedGoogle Scholar
  17. 17.
    Mathias JR, Fernandez A, Sninsky CA, Clench MH, Davis RH. Nausea, vomiting and abdominal pain after Roux-en-Y anastomosis: motility of the jejuna) limb. Gastroenterology 1985;88:101–107.PubMedGoogle Scholar
  18. 18.
    Ehrlein HJ, Wulschke S, Thoma G, Schumpelick V. Gastrointestinal motility and gastric emptying after Billroth Il gastrectomy in dogs. Dig Dis Sci 1989;34(g):1199–1210.PubMedCrossRefGoogle Scholar
  19. 19.
    Reppas C, Meyer JH, Sims PJ, Dressman JB. Effect of hydroxypropylmethylcellulose on gastrointestinal transit and luminal viscosity in dogs. Gastroenterology 1991; 100: 217–1223.Google Scholar
  20. 20.
    Horn S, Saff MG, Kelly KA, Hench V. Postoperative gastric stony after vagotomy for obstructing peptic ulcer. Am J Surg 1989; 1 57:282–286.Google Scholar
  21. 21.
    Goldberg KB, Lasichak A, Rock CL. Dietary adequacy in patients with diabetic gastroparesis. Journal of the American Dietetic Association. 1997;97(4):420–2.PubMedCrossRefGoogle Scholar
  22. 22.
    Thumshim M. Bruninga K. Camilleri M. Simplifying the evaluation of postprandial antral motor function in patients with suspected gastroparesis. Am J Gastroenter. 1997;92(9):1496–500.Google Scholar
  23. 23.
    Malagelada JR Distrutti E. Management of gastrointestinal motility disorders. A practical guide and appropriate ancillary measures. Review Drugs 1996;52:494–506.Google Scholar
  24. 24.
    Soergel KH. Greenberger NJ. Nausea and vomiting in the diabetic patient. Hospital Practice (Office Edition). 1998;33(2):43–5, 49–50, 56–61; discussion 61–2.Google Scholar
  25. 25.
    Oh JJ, Kim CH. Gastroparesis after a presumed viral illness: clinical and laboratory features and natural history. Mayo Clin Proc 1990;65:636–6642.PubMedCrossRefGoogle Scholar
  26. 26.
    Meeroff JC, Schreiber DS, Trier JS, Blacklow NR. Abnormal gastric motor function in viral gastroenteritis. Ann Intern Med 1980;92:370–373.PubMedGoogle Scholar
  27. 27.
    Nowak TV, Anuras S, Brown BP, Lonasescu V, Green JB. Small intestinal motility in myotonic dystrophy patients. Gastroenterology 1984;86:808–813.PubMedGoogle Scholar
  28. 28.
    Maddem GJ, Horowitz M, Jamieson GG, Chatterton BE, Collins PJ, Roberts-Thompson P. Abnormalities of esophageal and gastric emptying in progressive systemic sclerosis. Gastroenterology 1984;87:922–926.Google Scholar
  29. 29.
    Raffin SB. Bezoars. In: Sleisenger MH, Fordtran JS, eds. Gastrointestinal Disease, Vol 1, Philadelphia:WB Saunders, 1989:741–744.Google Scholar
  30. 30.
    Horowitz M, McNeill JD, Maddem GJ, Collins Pi, Shearman DJC. Abnormalities of gastric and esophageal emptying in polymyositis and dermatomyositis. Gastroenterology 1986;90:434.PubMedGoogle Scholar
  31. 31.
    Ikeda SI, Makishita H, Oguchi K, Yanagisawa N, Nagata T. Gastrointestinal amyloid deposition in familial amyloid polyneuropathy. Neurology (NY) 1982;32:1364–1368.CrossRefGoogle Scholar
  32. 32.
    Schulze-Delrieu K. Metoclopramide. In: Koch-Weser J, ed. Drug Therapy. N Engl J Med 1981; 305(1):28–33.Google Scholar
  33. 33.
    Brown CK, Khanderia U. Use of metoclopramide, domperidone and cisapfide in the management of diabetic gastroparesis. Clin Pharm 1990;9:357–365.Google Scholar
  34. 34.
    Janssens J, Peeters TL, Vantrappen G, et al. Improvement of gastric emptying in diabetic gastroparesis by erythromycin. N Engl J Med 1990;322(15):1028–1031.PubMedCrossRefGoogle Scholar
  35. 35.
    Mozwecz H, Pavel D, Pitrak D, Orellana P, Schlesinger PK, Leyden TJ. Erythromycin stcoratc as prokinetic agent in postvagotomy gastroparesis. Dig Dis Sci 1990;35(7):902–905.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Konrad Schulze-Delrieu
    • 1
  1. 1.University of Iowa College of MedicineIowa CityUSA

Personalised recommendations