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Combinatorial Chemistry: Part of the Evolution in Drug Discovery

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Current Trends in Organic Synthesis

Abstract

Combinatorial chemistry, automated synthesis, high-throughput screening, the explosion of molecular targets from genomic research and advances in informatics have come together in an interdependent evolution to provide an enormous opportunity not only for the life sciences but also for the materials sciences as well. Drug discovery has been the initial focus of this revolution because high-speed chemistry has rapidly evolved to meet the compound demands of high throughput, low volume screening which had been put in place to support the mechanistic based targets from molecular biology.

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Author information

Authors and Affiliations

  1. Pharmacopeia, Inc., 3000 Eastpark Boulevard, Cranbury, NJ, 08512, USA

    John J. Baldwin, Jonathan J. Burbaum & Nolan Sigal

Authors
  1. John J. Baldwin
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  2. Jonathan J. Burbaum
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  3. Nolan Sigal
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Editor information

Editors and Affiliations

  1. University of Milan, Milan, Italy

    Carlo Scolastico  & Francecso Nicotra  & 

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© 1999 Springer Science+Business Media New York

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Baldwin, J.J., Burbaum, J.J., Sigal, N. (1999). Combinatorial Chemistry: Part of the Evolution in Drug Discovery. In: Scolastico, C., Nicotra, F. (eds) Current Trends in Organic Synthesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4801-0_9

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  • DOI: https://doi.org/10.1007/978-1-4615-4801-0_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7175-5

  • Online ISBN: 978-1-4615-4801-0

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