Abstract
The second most abundant protein in human cerebrospinal fluid after albumin, named β-trace, has been recently identified to be lipocalin-type prostaglandin (PG) D synthase ((5Z,13E)-(15S)-9α, 11α-epidioxy-15-hydroxyprosta-5,13-dienoate-D-isomerase, EC 5.3.99.2)2. This enzyme catalyzes the conversion of PGH2 to PGD2 and is localized to the central nervous system3,4 and male genital organs of mammals5.
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Beuckmann, C.T., Urade, Y., Hayaishi, O. (1999). Lipocalin-type Prostaglandin D Synthase (β-Trace) Binds Non- Substrate Lipophilic Ligands. In: Honn, K.V., Marnett, L.J., Nigam, S., Dennis, E.A. (eds) Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4. Advances in Experimental Medicine and Biology, vol 469. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4793-8_9
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DOI: https://doi.org/10.1007/978-1-4615-4793-8_9
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