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Perspectives on Biologically Based Cancer Risk Assessment pp 1–20Cite as

Introduction

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Part of the book series: Nato · Challenges of Modern Society ((NATS,volume 23))

Abstract

Chemical carcinogens represent a variety of (classes of) substances that are present in different media and compartments, which are determined by their sources, applications and use. With respect to dose-response assessment, within the context of quantitative risk assessment (QRA), these carcinogens are evaluated by various bodies, either on a national or international basis or both. For those chemicals present in air and water, an international harmonization of this risk evaluation is strived for by the Quality Guidelines of the World Health Organization (WHO, 1987, 1993). The same holds for food additives, contaminants, and pesticides, allowable levels of which are based on ADIs (allowable daily intakes) determined by the FAO/WHO committees JECFA and JMPR, respectively.

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Author information

Authors and Affiliations

  1. U.S. Environmental Protection Agency, Washington, DC, USA

    V. J. Cogliano

  2. Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, The Netherlands

    E. D. Kroese

  3. National Institute of Health, Rome, Italy

    G. A. Zapponi, L. Attias & I. Marcello

Authors
  1. V. J. Cogliano
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  2. E. D. Kroese
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  3. G. A. Zapponi
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  4. L. Attias
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  5. I. Marcello
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Editor information

Editors and Affiliations

  1. United States Environmental Protection Agency, Washington, DC, USA

    Vincent James Cogliano

  2. Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

    E. Georg Luebeck

  3. National Institute of Health, Rome, Italy

    Giovanni A. Zapponi

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© 1999 Springer Science+Business Media New York

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Cogliano, V.J., Kroese, E.D., Zapponi, G.A., Attias, L., Marcello, I. (1999). Introduction. In: Cogliano, V.J., Luebeck, E.G., Zapponi, G.A. (eds) Perspectives on Biologically Based Cancer Risk Assessment. Nato · Challenges of Modern Society, vol 23. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4741-9_1

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  • DOI: https://doi.org/10.1007/978-1-4615-4741-9_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7149-6

  • Online ISBN: 978-1-4615-4741-9

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