Optical Mapping of Arrhythmias

  • Gregory E. Morley
  • Dhananjay Vaidya
  • José Jalife
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 231)

Abstract

Optical mapping of voltage dependent fluorescence in cardiac tissue allows for the simultaneous measurement of membrane potential from many locations on the surface of the heart. The development of this technology has revolutionized the field of cardiac electrophysiology and has provided new insights into the mechanisms of initiation and maintenance of cardiac arrhythmias (1–4). Recently, we have adopted this technology to image electrical activation in the hearts of normal and transgenic mice (5–7). By combining these novel technologies we hope to learn more about the roles of specific gene products in the development of cardiac arrhythmias.

Keywords

Anisotropy Pyridinium Syringe Cardiomyopathy Tetracycline 

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Copyright information

© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Gregory E. Morley
    • 1
  • Dhananjay Vaidya
    • 1
  • José Jalife
    • 1
  1. 1.Dept. of PharmacologySUNY Health Science CenterSyracuseUSA

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