Abstract
Throughout the industrialized world, as reported in the United States, Japan, and western Europe, diabetes mellitus is the leading cause of end-stage renal disease (ESRD). According to the United States Renal Data System (USRDS) 1999 Report, of 79,102 patients begun on therapy for ESRD during 1997, 33,096 (44.4%) had diabetes, an incidence rate of 120 per million population (USRDS, 1999) (figure 41-1). Once begun on treatment, whether by dialysis or a kidney transplant, diabetic patients suffer a higher death rate compared to other causes of ESRD, resulting in their lower prevalence among U.S. diabetic ESRD patients (on December 31, 1997) of 33.2% (100,892 of 304,083 patients) [1]. Glomerulonephritis and hypertensive renal disease rank below diabetes in incidence of ESRD patients, substantiating Mauer and Chavers’s early recognition in 1985 that “Diabetes is the most important cause of ESRD in the Western world [2]”
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Friedman, A.L., Friedman, E.A. (2000). Renal Transplantation for Diabetic Nephropathy. In: Mogensen, C.E. (eds) The Kidney and Hypertension in Diabetes Mellitus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4499-9_41
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