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Graves’ Disease pp 127–138Cite as

Animal Models of Graves’ Disease

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Part of the book series: Endocrine Updates ((ENDO,volume 6))

Abstract

It will be evident to the reader, from other chapters in this book, that Graves’ Disease (GD) is polygenic and multifactorial, a combination which makes unravelling relevant pathogenic mechanisms exceedingly difficult. GD is very common but patients present when disease has advanced to the extent of causing clinical signs and symptoms, which is likely to be temporally removed from the initiating immune events. Thus it has long been recognized that fundamental progress in our understanding of GD would benefit from an appropriate animal model.

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Authors
  1. Marian Ludgate
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  2. Sabine Costagliola
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  3. Gilbert Vassart
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Editor information

Editors and Affiliations

  1. Autoimmune Disease Unit, Cedars-Sinai Research Institute and U.C.L.A. School of Medicine, Los Angeles, California, USA

    Basil Rapoport M.B., Ch.B.  & Sandra M. McLachlan Ph.D  & 

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© 2000 Springer Science+Business Media New York

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Ludgate, M., Costagliola, S., Vassart, G. (2000). Animal Models of Graves’ Disease. In: Rapoport, B., McLachlan, S.M. (eds) Graves’ Disease. Endocrine Updates, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4407-4_9

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  • DOI: https://doi.org/10.1007/978-1-4615-4407-4_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6983-7

  • Online ISBN: 978-1-4615-4407-4

  • eBook Packages: Springer Book Archive

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