Insect Growth Regulators

  • Herbert Oberlander
  • Donald L. Silhacek


Biologists in the early part of the 20th century believed that since the secondary sexual characteristics of insects were unaffected by castration, insects did not secrete hormones. This view was challenged by the conclusive experiments of Stephan Kopeç in 1917, who showed by surgical maneuver, that insect metamorphosis was under the hormonal control of the brain. Over the next half- century, significant discoveries in insect endocrinology were made by such pioneers as Wigglesworth, Bodenstein, Fukuda, and Williams, among others (see review by Granger and Bollenbacher 1981). The classical scheme that was developed by these scientists was that a hormone from the brain, now known as prothracicotropic hormone (PTTH), stimulated the prothoracic glands to release a molting hormone (ecdysteroid), which caused either molting or metamorphosis depending upon the stage of the insect, and in particular, on whether a third hormone, juvenile hormone (JH), was present.


Juvenile Hormone Insect Growth Regulator Chitin Synthesis Prothoracic Gland Juvenile Hormone Analogue 
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© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Herbert Oberlander
  • Donald L. Silhacek

There are no affiliations available

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