Paired Filtration Dialysis (PFD):Biocompatibility and Depurative Efficiency
Biocompatibility and depurative efficiency of Paired Filtration Dialysis was evaluated in a short-term (one month) follow up in 12 chronic uremic patients. Plasma granulocyte elastase slightly increased during the first hour of treatment, a transient but significative leukopenia was observed.Protein layer revealed a marked deposition of coagulation factors on polysulphone and trace amount of C3c and immunoglobulins on Hemophane. PFD allows an high depurative efficiency for small molecules (assessed by a Kt/V urea >1) and for Beta-2 MG even in a shorter dialytic time.
KeywordsRenal Unit Granulocyte Count Dialytic Time Granulocyte Elastase Frustrate Phagocytosis
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