Paired Filtration Dialysis (PFD):Biocompatibility and Depurative Efficiency

  • V. Panichi
  • A. M. Bianchi
  • M. Parrini
  • L. Casarosa
  • G. Grazi
  • E. Montagnani
  • M. Aloisi
  • P. Ferrandello
  • R. Menicucci
  • A. Baronti
  • R. Cominotto
  • A. Rossi
Chapter
Part of the Developments in Nephrology book series (DINE, volume 30)

Abstract

Biocompatibility and depurative efficiency of Paired Filtration Dialysis was evaluated in a short-term (one month) follow up in 12 chronic uremic patients. Plasma granulocyte elastase slightly increased during the first hour of treatment, a transient but significative leukopenia was observed.Protein layer revealed a marked deposition of coagulation factors on polysulphone and trace amount of C3c and immunoglobulins on Hemophane. PFD allows an high depurative efficiency for small molecules (assessed by a Kt/V urea >1) and for Beta-2 MG even in a shorter dialytic time.

Keywords

Filtration Convection Urea Lactate Isothiocyanate 

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Copyright information

© Springer Science+Business Media Dordrecht 1991

Authors and Affiliations

  • V. Panichi
    • 1
  • A. M. Bianchi
    • 1
  • M. Parrini
    • 1
  • L. Casarosa
    • 1
  • G. Grazi
    • 1
  • E. Montagnani
    • 1
  • M. Aloisi
    • 1
    • 2
  • P. Ferrandello
    • 1
    • 2
  • R. Menicucci
    • 1
    • 3
  • A. Baronti
    • 1
    • 3
  • R. Cominotto
    • 1
    • 3
  • A. Rossi
    • 1
    • 4
  1. 1.II Medical Clinic InstituteUniversity of PisaItaly
  2. 2.Renal UnitPietrasantaItaly
  3. 3.Renal UnitPiombinoItaly
  4. 4.Renal UnitMontecatiniItaly

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