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Paired Filtration Dialysis (PFD):Biocompatibility and Depurative Efficiency

  • V. Panichi
  • A. M. Bianchi
  • M. Parrini
  • L. Casarosa
  • G. Grazi
  • E. Montagnani
  • M. Aloisi
  • P. Ferrandello
  • R. Menicucci
  • A. Baronti
  • R. Cominotto
  • A. Rossi
Chapter
Part of the Developments in Nephrology book series (DINE, volume 30)

Abstract

Biocompatibility and depurative efficiency of Paired Filtration Dialysis was evaluated in a short-term (one month) follow up in 12 chronic uremic patients. Plasma granulocyte elastase slightly increased during the first hour of treatment, a transient but significative leukopenia was observed.Protein layer revealed a marked deposition of coagulation factors on polysulphone and trace amount of C3c and immunoglobulins on Hemophane. PFD allows an high depurative efficiency for small molecules (assessed by a Kt/V urea >1) and for Beta-2 MG even in a shorter dialytic time.

Keywords

Renal Unit Granulocyte Count Dialytic Time Granulocyte Elastase Frustrate Phagocytosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media Dordrecht 1991

Authors and Affiliations

  • V. Panichi
    • 1
  • A. M. Bianchi
    • 1
  • M. Parrini
    • 1
  • L. Casarosa
    • 1
  • G. Grazi
    • 1
  • E. Montagnani
    • 1
  • M. Aloisi
    • 1
    • 2
  • P. Ferrandello
    • 1
    • 2
  • R. Menicucci
    • 1
    • 3
  • A. Baronti
    • 1
    • 3
  • R. Cominotto
    • 1
    • 3
  • A. Rossi
    • 1
    • 4
  1. 1.II Medical Clinic InstituteUniversity of PisaItaly
  2. 2.Renal UnitPietrasantaItaly
  3. 3.Renal UnitPiombinoItaly
  4. 4.Renal UnitMontecatiniItaly

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