Paired Filtration Dialysis (PFD):Biocompatibility and Depurative Efficiency
Biocompatibility and depurative efficiency of Paired Filtration Dialysis was evaluated in a short-term (one month) follow up in 12 chronic uremic patients. Plasma granulocyte elastase slightly increased during the first hour of treatment, a transient but significative leukopenia was observed.Protein layer revealed a marked deposition of coagulation factors on polysulphone and trace amount of C3c and immunoglobulins on Hemophane. PFD allows an high depurative efficiency for small molecules (assessed by a Kt/V urea >1) and for Beta-2 MG even in a shorter dialytic time.
KeywordsFiltration Convection Urea Lactate Isothiocyanate
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- l).Ghezzi, P.M., Sanz-Moreno C., Gervasio,., Nigrelli, S., Botella, J. Trans ASAIO 33:546–550, 1987.Google Scholar
- 2).Panichi, V., Bianchi, A.M.. Casarosa, L.. Cominotto, R., Parrini, M., Grazi, G., Cirami, C., Palla, R. In: Advances in Biomaterials, Volume 8, Elsevier Science Publishers B.V., Amsterdam pag. 193–200, 1988.Google Scholar