Prostaglandins, Radiation, and Thermoregulation

Abstract

Changes in body temperature can be observed after radiation exposure (1), an effect that depends on the species being used. For example, radiation induces hyperthermia in cats, rabbits (2), and humans (3); a biphasic response in monkeys (a fall followed by a rise (4)); a dual effect in rats (low and high doses produce hyperthermia and hypothermia, respectively (5)); and hypothermia in guinea pigs (6). However, the mechanisms underlying hyperthermia and hypothermia due to radiation are unknown.