Prostaglandins, Radiation, and Thermoregulation

  • S. B. Kandasamy
  • W. A. Hunt
Chapter
Part of the Developments in Oncology book series (DION, volume 67)

Abstract

Changes in body temperature can be observed after radiation exposure (1), an effect that depends on the species being used. For example, radiation induces hyperthermia in cats, rabbits (2), and humans (3); a biphasic response in monkeys (a fall followed by a rise (4)); a dual effect in rats (low and high doses produce hyperthermia and hypothermia, respectively (5)); and hypothermia in guinea pigs (6). However, the mechanisms underlying hyperthermia and hypothermia due to radiation are unknown.

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References

  1. 1.
    Kimeldorf, D.J. and Hunt, E.L. In: Ionizing Radiation: Neural Function and Behavior (Eds. D.J. Kimeldorf and E.L. Hunt), New York, 1965, pp. 109–130.Google Scholar
  2. 2.
    Veninga, T.S. Radiat. Res. 48: 358–367, 1971.PubMedCrossRefGoogle Scholar
  3. 3.
    Fanger, H. and Lushbaugh, C.C. Arch. Pathol. 83: 446–460, 1967.PubMedGoogle Scholar
  4. 4.
    McFarland, W.L. and Willis, J.A. Cerebral temperature changes in the monkey (Macaca mulatta) after 2500 rads ionizing radiation. Armed Forces Radiobiology Res. Inst. Scientific Report, SR 74–77,1974.Google Scholar
  5. 5.
    Kandasamy, S.B., Hunt, W.A. and Mickley, G.A. Radiat. Res. 114: 42–53, 1988.PubMedCrossRefGoogle Scholar
  6. 6.
    Kandasamy, S.B. and Hunt, W.A. Life Sci. 42: 555–563, 1988.PubMedCrossRefGoogle Scholar
  7. 7.
    Feldberg, W. and Milton, S. In: Inflammation (Eds. J.R. Vane and S.H. Ferreira), Springer-Verlag, New York, 1978, pp. 617–656.CrossRefGoogle Scholar
  8. 8.
    Milton, A.S. and Wendlandt, S.J. Physiol. 218: 325–336, 1971.Google Scholar
  9. 9.
    Clark, W.G. and Lipton, J.M. Neurosci. Biobehav. Rev. 9: 479–552, 1985.PubMedCrossRefGoogle Scholar
  10. 10.
    Clark, W.G. and Lipton, J.M. Neurosci. Biobehav. Rev. 18: 299–371, 1985.CrossRefGoogle Scholar
  11. 11.
    Lasser, E.C. and Stenstrom, K.W. Am. J. Roentgenol. 72: 985–988, 1954.Google Scholar
  12. 12.
    Cockerham, L.G., Doyle, T.F., Donlon, M.A. and Helgeson, E.A. Aviat. Space Environ. Med. 55: 1041–1045, 1984.PubMedGoogle Scholar
  13. 13.
    Alter, W.A., Hawkins, R.N., Catravas, G.N., Doyle, T.F. and Takenaga, J.K. Radiat. Res. 94: 654, 1983.Google Scholar
  14. 14.
    Cockerham, L.G., Cerveny, T.J. and Hampton, D.J. Aviat. Space Environ. Med. 57: 578–582, 1986.PubMedGoogle Scholar
  15. 15.
    Doyle, T.F., Turns, J.E. and Strike, T.A. Aerospace Med. 42: 400–403, 1971.PubMedGoogle Scholar
  16. 16.
    Adam, H.M. and Hye, H.K.A. Br. J. Pharmacol. 28:137–152, 1966.Google Scholar
  17. 17.
    Lipinski, J.F., Schaumburg, H. and Baldessarini, R.J. Brain Res. 52: 403–408, 1973.PubMedCrossRefGoogle Scholar
  18. 18.
    Snyder, S.H. and Taylor, K.M. In: Perspectives in Neuropharmacology (Ed. S.H. Snyder), New York, 1972, pp. 43–73.Google Scholar
  19. 19.
    Lomax, P. and Green, M.D. In: Temperature: Regulation, Drug Effects, and Therapeutic Implications (Eds. P. Lomax and E. Schonbaum), New York, 1979, pp. 289–304.Google Scholar
  20. 20.
    Kandasamy, S.B., Kumar, K.S., Hunt, W.A. and Weiss, J.F. Radiat. Res. 114:240–247, 1988.PubMedCrossRefGoogle Scholar
  21. 21.
    Kandasamy, S.B. and Hunt, W.A. In: Thermoregulation: Research and Clinical Applications (Eds. Lomax and Schonbaum), Karger, Basel, 1989, pp. 116–119.Google Scholar
  22. 22.
    Kandasamy, S.B. and Hunt, W.A. Radiat. Res. 1990, 121:84–90.PubMedCrossRefGoogle Scholar
  23. 23.
    Pausescu, E., Chirvasie, R., Teodosiu, T. and Paun, C. Radiat. Res. 65:163–171,1976.PubMedCrossRefGoogle Scholar
  24. 24.
    Vane, J.R. Nature 231: 232–235, 1971.Google Scholar
  25. 25.
    Mickley, G.A., Stevens, K.E., Moore, G.H., Deere, W., White, G.A., Gibbs, G.L. and Mueller, G.P. Pharmacol. Biochem. Behav. 19: 979–983, 1983.PubMedCrossRefGoogle Scholar
  26. 26.
    Collier, H.O.J., McDonald-Gibson, W.J. and Sneed, S.A. Br. J. Pharmacol. 52:116P, 1974.PubMedGoogle Scholar
  27. 27.
    Edvinsson, L., Cervos-Navarrp, J., Larrson, L., Owman, C.H. and Ronnberg, A.L. Neurol. 27: 878–883,1977.CrossRefGoogle Scholar
  28. 28.
    Abdel-Halim, M.S., Hamberg, M., Sjoquist, B. and Anggard, E. Prostaglandins 14: 633–643, 1977.PubMedCrossRefGoogle Scholar
  29. 29.
    Forestermann, U., Heldt, R., Knappen, F. and Hertting, G. Brain Res. 240: 303–310, 1982.CrossRefGoogle Scholar
  30. 30.
    Kawabe, H., Hayashi, H. and Hayaishi, O. Biochem. Biophys. Res. Commun. 143: 467–474, 1987.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • S. B. Kandasamy
    • 1
  • W. A. Hunt
    • 1
  1. 1.Behavioral Sciences DepartmentArmed Forces Radiobiology Research InstituteBethesdaUSA

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