Radiation Protection and Cancer Therapy by Linoleate
Linoleate (LA) injected i.p. into mice one day after the inoculation of Ehrlich ascites tumor cells prevented the growth of the tumor (1). It also protected mouse bone marrow cells against radiation damage even when injected an hour or more after exposure of the mice to gamma rays (2). It seems likely, therefore, that combined radiation and LA therapy may be useful for the control of selected cancers. We have begun an investigation of the combined therapy both by clinical studies of the safety and efficacy of LA therapy in 41 dogs and 12 cats with advanced cancer and by laboratory studies.
KeywordsToxicity Lymphoma Sarcoma Diarrhea Glutamine
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