Abstract
Immunological adjuvants can be defined as substances which are not specific to a particular antigen, but which can enhance the specific immune response to antigens. In recent years a new group of such molecules has been defined and partially characterised. These are non-antigen specific molecules which affect specific immune responses in various ways — the cytokines. The increasing availability of cytokines in purified form, as recombinant proteins, has enabled a much increased understanding of their actions and, among many other things, has revealed their usefulness as adjuvants.
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Heath, A.W., Playfair, J.H.L. (1991). Effects of Added Cytokines on Immune Responses and Memory. In: Gregoriadis, G., Allison, A.C., Poste, G. (eds) Vaccines. NATO ASI Series, vol 215. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3848-6_8
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