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Immunology of Milk and the Neonate pp 159–165Cite as

The Role of Milk-Derived Antimicrobial Lipids as Antiviral and Antibacterial Agents

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Part of the Advances in Experimental Medicine and Biology book series (AEMB,volume 310)

Abstract

Milk lipids are not only nutrients but also non-immunoglobulin protective factors1–3. The lipids in human milk do not initially have antimicrobial activity, but become antiviral2, antibacteria14,5 and antiprotozoal6 in vitro following storage and in vivo following digestion in the gastrointestinal tract of the milk-fed infant2,5,7. Microbial killing by milk lipids is due primarily to free fatty acids (FFAs) and monoglycerides (MGs) released from milk triglycerides by lipases and can be duplicated using purified FFAs and MGs8,9.

Keywords

  • Antiviral Activity
  • Milk Sample
  • Human Milk
  • Stomach Content
  • Envelop Virus

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Author information

Authors and Affiliations

  1. Department of Developmental Biochemistry, Institute for Basic Research, NY, 10314, Staten Island, USA

    Charles E. Isaacs

  2. Institute of Biology, University of Iceland, Reykjavik, Iceland

    Halldor Thormar

Authors
  1. Charles E. Isaacs
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  2. Halldor Thormar
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky

  2. National Institutes of Health, Bethesda, Maryland, USA

    Claudia Blair

  3. University of Texas, Galveston, Texas, USA

    Pearay L. Ogra

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© 1991 Springer Science+Business Media New York

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Isaacs, C.E., Thormar, H. (1991). The Role of Milk-Derived Antimicrobial Lipids as Antiviral and Antibacterial Agents. In: Mestecky, J., Blair, C., Ogra, P.L. (eds) Immunology of Milk and the Neonate. Advances in Experimental Medicine and Biology, vol 310. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3838-7_19

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  • DOI: https://doi.org/10.1007/978-1-4615-3838-7_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6713-0

  • Online ISBN: 978-1-4615-3838-7

  • eBook Packages: Springer Book Archive

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