Abstract

Aneuploidy, the change in chromosome number by the addition (trisomy) or loss (monosomy) of a single chromosome, has a most dramatic effect on the cells and organisms in which it occurs. It is extremely harmful because it changes the gene dosages and creates genetic imbalances of a large number of genes simultaneously.

Keywords

Recombination Dementia Fibril Infertility Colchicine 

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Judith H. Ford
    • 1
  1. 1.Genetics DepartmentThe Queen Elizabeth HospitalWoodvilleAustralia

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