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Clinical Application of Tissue Plasminogen Activator Therapy in Acute Myocardial Infarction

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Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 281))

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Abstract

Acute myocardial infarction is related to plaque rupture and thrombosis formation in the infarct-related coronary artery. Salvage of ischemic area with thrombolysis in the early stage of infarction has proved to be the best way to limit infarct size, preserve left ventricular function and reduce mortality in the majority of victims. Tissue plasminogen activator (tPA) is the most promising thrombolytic agent used to salvage ischemic myocardium; the efficacy has been systematically demonstrated in previous studies (1–4).

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© 1990 Springer Science+Business Media New York

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Wang, SP., Chang, MS., Chiang, B.N. (1990). Clinical Application of Tissue Plasminogen Activator Therapy in Acute Myocardial Infarction. In: Liu, C.Y., Chien, S. (eds) Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis. Advances in Experimental Medicine and Biology, vol 281. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3806-6_42

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  • DOI: https://doi.org/10.1007/978-1-4615-3806-6_42

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6697-3

  • Online ISBN: 978-1-4615-3806-6

  • eBook Packages: Springer Book Archive

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