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The Paramyxoviruses pp 249–274Cite as

The Role of Viral and Host Cell Proteins in Paramyxovirus Transcription and Replication

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Part of the book series: The Viruses ((VIRS))

Abstract

The viruses of the Paramyxoviridae family contain a nonsegmented RNA genome of the negative (−)-strand sense [for earlier reviews see Kingsbury (1977), Choppin and Compans (1975), Kolakofsky and Roux (1987)]. In the case of Sendai virus, the prototype of the family, the genome RNA and its full-length complement, the antigenome RNA, are found both in the virion and in the infected cell as an RNase-resistant nucleocapsid due to the tight association of the major nucleocapsid protein, NP (M r 57, 000) with the RNA. Two other viral proteins, the P (M r 79, 000) and L (M r 240, 000) proteins, are associated less tightly with the nucleocapsid and function as subunits of the RNA-dependent RNA polymerase. Three additional viral proteins, the hemagglutinin-neuraminidase (HN, M r 72, 000, fusion (F o, M r 65, 000), and matrix (M, M r 34, 000) proteins, are associated with the lipid envelope of the virion.

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References

  • Alkhatib, G., and Briedis, D.J., 1986, The predicted primary structure of the measles virus hemagglutinin, Virology 150:479–490.

    PubMed  CAS  Google Scholar 

  • Baker, S. C., and Moyer, S. A., 1988, Encapsidation of Sendai virus genome RNAs by purified NP protein during in vitro replication, J. Virol. 62:834–838.

    PubMed  CAS  Google Scholar 

  • Banerjee, A. K., 1987, Transcription and replication of rhabdoviruses, Microbiol. Rev. 51:66–87.

    PubMed  CAS  Google Scholar 

  • Bellini, W. J., Englund, G., Rozenblatt, G., Arnheiter, H., and Richardson, C. D., 1985, Measles virus P gene codes for two proteins, J. Virol. 53:908–919.

    PubMed  CAS  Google Scholar 

  • Bellini, W. J., Englund, G., Richardson, C. D., Rozenblatt, S., and Lazzarini, R. A., 1986, Matrix genes of measles virus and canine distemper virus: Cloning, nucleotide sequences and deduced amino acid sequences, J. Virol. 58:408–416.

    PubMed  CAS  Google Scholar 

  • Bernard, J. P., and Northrop, R. L., 1974, RNA polymerase activity in mumps virus, J. Virol. 14:183–186.

    PubMed  CAS  Google Scholar 

  • Blumberg, B. M., and Kolakofsky D., 1981, Intracellular vesicular stomatis virus leader RNAs are found in nucleocapsid structures, J. Virol. 40:568–576.

    PubMed  CAS  Google Scholar 

  • Blumberg, B. M., Leppert, M., and Kolakofsky, D., 1981, Interaction of VSV leader RNA and nucleocapsid protein may control VSV genome replication, Cell 23:837–845.

    PubMed  CAS  Google Scholar 

  • Blumberg, B. M., Giorgi, C., and Kolakofsky, D., 1983, N protein of vesicular stomatitis virus selectively encapsidates leader RNA in vitro, Cell 32:559–657.

    PubMed  CAS  Google Scholar 

  • Blumberg, B. M., Giorgi, C., Rose, K., and Kolakofsky, D., 1984. Preparation and analysis of the nucleocapsid proteins of vesicular stomatitis virus and Sendai virus, and analysis of the Sendai virus leader NP gene region, J. Gen. Virol. 65:769–779.

    PubMed  CAS  Google Scholar 

  • Blumberg, B. M., Crowley, J. C., Silverman, J. I., Menonna, J., Cook, S. D., and Dowling, P. C. 1988, Measles virus L protein evidences elements of ancestral RNA polymerase, Virology 164:487–497.

    PubMed  CAS  Google Scholar 

  • Bohn, W., Rutter, G., Hohenberg, H., Mannweiler, K., and Nobis, P., 1986, Involvement of actin filaments in budding of measles virus: Studies on cytoskeletons of infected cells, Virology 149:91–106.

    PubMed  CAS  Google Scholar 

  • Buetti, E., and Choppin, P. W., 1977, The transcriptase complex of paramyxovirus SV5, Virology 82:493–508.

    PubMed  CAS  Google Scholar 

  • Carlsen, S. R., Peluso, R. W., and Moyer, S. A., 1985, In vitro replication of Sendai virus wild type and defective interferring particle genome RNAs, J. Virol. 54:493–500.

    PubMed  CAS  Google Scholar 

  • Carroll, A. R., and Wagner, R. R., 1979, Role of the membrane (M) protein in endogenous inhibition of in vitro transcription of vesicular stomatitis virus, J. Virol. 29:134–142.

    PubMed  CAS  Google Scholar 

  • Castaneda, S. J., and Wong, T. C., 1989, Measles virus synthesizes both leaderless and leader-containing polyadenylated RNAs in vivo, J. Virol. 63:2977–2986.

    PubMed  CAS  Google Scholar 

  • Cattaneo, R., Rebmann, G., Schmid, A., Baczko, K., ter Meulen, V., and Billeter, M. A., 1987, Altered transcription of a defective measles virus genome derived from a diseased human brain, EMBO J. 6:681–688.

    PubMed  CAS  Google Scholar 

  • Cattaneo, R., Kaelin, K., Baczko, K., and Billeter, M. A., 1989, Measles virus editing provides an additional cysteine-rich protein, Cell 56:759–764.

    PubMed  CAS  Google Scholar 

  • Cervera, M., Dreyfuss, G., and Penman, S., 1981, Messenger RNA is translated when associated with the cytoskeletal framework in normal and VSV-infected HeLa cells, Cell 23:113–120.

    PubMed  CAS  Google Scholar 

  • Chatterjee, P. K., Cervera, M. M., and Penman, S., 1984, Formation of vesicular stomatitis virus nucleocapsid from cytoskeletal framework-bound N protein: Possible model for structural assembly, Mol. Cell. Biol. 4:2231–2234.

    PubMed  CAS  Google Scholar 

  • Chattopadhyay, D., and Banerjee, A. K., 1987, Two separate domains within vesicular stomatitis virus phosphoprotein support transcription when added in trans, Proc. Natl. Acad. Sci. USA 84:8932–8936.

    PubMed  CAS  Google Scholar 

  • Chattopadhyay, D., and Banerjee, A. K., 1988, NH2-Terminal acidic region of the phosphoprotein of vesicular stomatitis virus can be functionally replaced by tubulin, Proc. Natl Acad. Sci. USA 85:7977–7981.

    PubMed  CAS  Google Scholar 

  • Chinchar, V. G., and Portner, A. 1981, Functions of Sendai virus nucleocapsid polypeptides: Enzymatic activities in nucleocapsids following cleavage of polypeptide P by Staphylococcus aureus protease V8, Virology 109:59–71.

    PubMed  CAS  Google Scholar 

  • Choppin, P. W., and Compans, R. W. 1975, Reproduction of paramyxoviruses, in “Comprehensive Virology,” Vol. 4 (H. Fraenkel-Conrat and R. R. Wagner, eds.), pp. 95–178, Plenum Press, New York.

    Google Scholar 

  • Clinton, G. M., Little, S. P., Hagen, F. S., and Huang, A. S., 1978, The matrix (M) protein of vesicular stomatitis virus regulates transcription, Cell 15:1455–1462.

    PubMed  CAS  Google Scholar 

  • Colonno, R. J., and Stone, H. O., 1975, Methylation of messenger RNA of Newcastle disease virus in vitro by a virion associated enzyme, Proc. Natl. Acad. Sci. USA 72:2611–2615.

    PubMed  CAS  Google Scholar 

  • Colonno, R. J., and Stone, H. O., 1976a, Isolation of a transcriptive complex from Newcastle disease virus, J. Virol. 19:1080–1089.

    PubMed  CAS  Google Scholar 

  • Colonno, R. J., and Stone, H. O., 1976b, Newcastle disease virus messenger RNA lacks 2′-O-methylated nucleotides, Nature 261:611–614.

    PubMed  CAS  Google Scholar 

  • Crowley, J. C., Dowling, P. C., Menonna, J., Silverman, J. I., Schuback, D., Cook, S. D., and Blumberg, B. M., 1988, Sequence variability and function of measles virus 3′ and 5′ ends and intercistronic regions, Virology 164:498–506.

    PubMed  CAS  Google Scholar 

  • Curran, J., and Kolakofsky, D., 1987, Identification of an additional Sendai virus non-structural protein encoded by the P/C mRNA, J. Gen. Virol. 68:2515–2519.

    PubMed  CAS  Google Scholar 

  • Curran, J., and Kolakofsky, D., 1988a, Ribosomal initiation from an ACG codon in the Sendai virus P/C mRNA, EMBO J. 7:245–251.

    PubMed  CAS  Google Scholar 

  • Curran, J., and Kolakofsky, D., 1988b, Scanning independent ribosomal initiation of the Sendai virus X protein, EMBO J. 7:2869–2874.

    PubMed  CAS  Google Scholar 

  • De, B. P., and Banerjee, A. K., 1985, Requirements and functions of vesicular stomatitis virus L and NS proteins in the transcription process in vitro, Biochem. Biophys. Res. Commun. 126:40–49.

    PubMed  CAS  Google Scholar 

  • Deshpande, K. L., and Portner, A., 1984, Structural and functional analysis of Sendai virus nucleocapsid NP protein with monoclonal antibodies, Virology 139:32–42.

    PubMed  CAS  Google Scholar 

  • Deshpande, K. L., and Portner, A., 1985, Monoclonal antibodies to the P protein of Sendai virus define its structure and role in transcription, Virology 140:125–134.

    PubMed  CAS  Google Scholar 

  • Dillon, P. J., and Gupta, K. C., 1989, Expression of five proteins from the Sendai virus P/C mRNA in infected cells, J. Virol. 63:974–977.

    PubMed  CAS  Google Scholar 

  • Dowling, P. C., Blumberg, B. M., Menonna, J., Adamus, J. E., Cook, P. J., Crowley, J. C., Kolakofsky, D., and Cook, S. D., 1986, Transcriptional map of the measles virus genome, J. Gen. Virol. 67:1987–1992.

    PubMed  CAS  Google Scholar 

  • Elango, N., Varsanyi, T., Kovamees, J., and Norrby, E., 1988, Molecular cloning and characterization of six genes, determination of gene order and intergenic sequences and leader sequence of mumps virus, J. Gen. Virol. 69:2893–2900.

    PubMed  CAS  Google Scholar 

  • Emerson, S. U., and Schubert, M., 1987, Location of the binding domains for the RNA polymerase L and the ribonucleocapsid template within different halves of the NS phosphoprotein of vesicular stomatitis virus, Proc. Natl. Acad. Sci. USA 84:5655–5659.

    PubMed  CAS  Google Scholar 

  • Etkind, P. R., Cross, R. K., Lamb, R. A., Merc, D. C., and Choppin, P. W., 1980, In vitro synthesis of structural and nonstructural proteins of Sendai and SVS viruses, Virology 100:22–33.

    PubMed  CAS  Google Scholar 

  • Feldhaus, A. L., and Lesnaw, J. A., 1988, Nucleotide sequence of the L gene of vesicular stomatitis virus (New Jersey): Identification of conserved domains in the New Jersey and Indiana L proteins, Virology 163:359–368.

    PubMed  CAS  Google Scholar 

  • Galinski, M. S., Mink, M. A., and Pons, M. W., 1988, Molecular cloning and sequence analysis of the human parainfluenza 3 virus gene encoding the L protein, Virology 165:499–510.

    PubMed  CAS  Google Scholar 

  • Gentry, N., and Busserau, F., 1980, Is cytoskeleton involved in vesicular stomatitis virus reproduction?, J. Virol. 34:777–781.

    Google Scholar 

  • Gerald, C., Buckland, R., Barker, R., Freeman, G., and Wild, T. F., 1986, Measles virus haemagglutinin gene: Cloning, complete nucleotide sequence analysis and expression in COS cells, J. Gen. Virol. 67:2695–2703.

    PubMed  CAS  Google Scholar 

  • Gill, D. S., Chattopadhyay, D., and Banerjee, A. K., 1986, Identification of a domain within the phosphoprotein of vesicular stomatitis virus that is essential for transcription in vitro, Proc. Natl. Acad. Sci. USA 83:8873–8877.

    PubMed  CAS  Google Scholar 

  • Gill, D. S., Takai, S., Portner, A., and Kingsbury, D. W., 1988, Mapping of antigenic domains of Sendai virus nucleocapsid protein expressed in Escherichia coli, J. Virol. 62:4805–4808.

    PubMed  CAS  Google Scholar 

  • Giuffre, R. M., Tovell, D. R., Kay, C. M., and Tyrrell, D. L. J., 1982, Evidence for an interaction between the membrane protein of a paramyxovirus and actin, J. Virol. 42:963–968.

    PubMed  CAS  Google Scholar 

  • Glazier, K., Raghow, R., and Kingsbury, D. W., 1977, Regulation of Sendai virus transcription: Evidence for a single promoter in vivo, J. Virol. 21:863–871.

    PubMed  CAS  Google Scholar 

  • Gupta, K. C., and Kingsbury, D. W., 1982, Conserved polyadenylation signals in two negative-strand RNA virus families, Virology 120:518–523.

    PubMed  CAS  Google Scholar 

  • Gupta, K. C., and Kingsbury, D. W., 1984, Complete sequences of the intergenic and mRNA start signals in the Sendai virus genome: Homologies with the genome of vesicular stomatitis virus, Nucleic Acids Res. 12:3829–3841.

    PubMed  CAS  Google Scholar 

  • Hall, W. W., and ter Meulen, V., 1977, Polyadenylic acid [poly(A)] sequences associated with measles virus intracellular ribonucleic acid (RNA) species, J. Gen. Virol. 35:497–510.

    Google Scholar 

  • Hamaguchi, M., Yoshida, T., Nishikawa, K., Naruse, H., and Nagai, Y., 1983, Transcriptive complex of Newcastle disease virus. I. Both L and P proteins are required to reconstitute an active complex, Virology 128:105–117.

    PubMed  CAS  Google Scholar 

  • Hamaguchi, M., Nishikawa, K., Toyoda, T., Yoshida, T., Hanaichi, T., and Nagai, Y., 1985, Transcriptive complex of Newcastle disease virus II. Structural and functional assembly associated with the cytoskeletal framework, Virology 147:295–308.

    PubMed  CAS  Google Scholar 

  • Heggeness, M. H., Scheid, A., and Choppin, P. W., 1981, The relationship of conformational changes in the Sendai virus nucleocapsid to proteolytic cleavage of the NP polypeptide, Virology 114:555–562.

    PubMed  CAS  Google Scholar 

  • Hercyk, N., Horikami, S. M., and Moyer, S. A., 1988, The vesicular stomatitis virus L protein possesses the mRNA methyltransferase activities, Virology 163:222–225.

    PubMed  CAS  Google Scholar 

  • Herman, R. C., 1989, Synthesis of respiratory syncytial virus RNA in cell-free extracts, J. Gen. Virol. 70:755–761.

    PubMed  CAS  Google Scholar 

  • Hill, V. M., Harmon, S. A., and Summers, D. F., 1986, Stimulation of vesicular stomatitus virus in vitro RNA synthesis by microtubule-associated proteins, Proc. Natl. Acad. Sci. USA 83:5410–5413.

    PubMed  CAS  Google Scholar 

  • Hsu, C.-H., and Kingsbury, D. W., 1982, Topography of phosphate residues in Sendai virus proteins, Virology 120:225–234.

    PubMed  CAS  Google Scholar 

  • Huang, A. S., Baltimore, D., and Bratt, M. A., 1971, Ribonucleic acid polymerase in virions of Newcastle disease virus: Comparison with vesicular stomatitis virus polymerase, J. Virol. 7:389–394.

    PubMed  CAS  Google Scholar 

  • Hunt, D. M., Smith, E. G., and Buckley, D. W., 1984, Aberrant polyadenylation by a vesicular stomatitis virus mutant is due to an altered L protein, J. Virol. 52:515–521.

    PubMed  CAS  Google Scholar 

  • Jambou, R. C., Elango, N., Vankatesan, S., and Collins, P. L., 1986, Complete sequence of the major nucleocapsid protein gene of human parainfluenza type 3 virus: Comparison with other negative strand viruses, J. Gen. Virol. 67:2543–2548.

    PubMed  CAS  Google Scholar 

  • Kingsbury, D. W., 1977, Paramyxoviruses, “The Molecular Biology of Animal Viruses,” Vol. 1, (D. P. Nayak, ed.), pp. 349–382, Marcel Dekker, New York.

    Google Scholar 

  • Kingsbury, D. W., Hsu, C. H., and Murti, K. G., 1978, Intracellular metabolism of Sendai virus nucleocapsids, Virology 91:86–94.

    PubMed  CAS  Google Scholar 

  • Kolakofsky, D., and Roux, L., 1987, The molecular basis of viral replication, in “The Molecular Biology of Paramyxoviruses” (R. Perez Bercoff, ed.), pp. 277–297, Plenum Press, New York.

    Google Scholar 

  • Krauhs, E., Little, M., Kempf, T., Hofer-Warbinek, R., Ade, W., and Ponstingl, H., 1981, Complete amino acid sequence of beta-tubulin from porcine brain, Proc. Natl. Acad. Sci. USA 78:4156–4160.

    PubMed  CAS  Google Scholar 

  • Kristensson, K., and Orvell, C., 1983, Cellular localization of five structural proteins of Sendai virus studied with peroxidase-labeled Fab fragments of monoclonal antibodies, J. Gen. Virol. 64:1673–1678.

    PubMed  Google Scholar 

  • Lamb, R. A., and Choppin, P. W., 1977, The synthesis of Sendai virus polypeptides in infected cells. II. Intracellular distribution of polypeptides, Virology 81:371–381.

    PubMed  CAS  Google Scholar 

  • Lamb, R. A., Mahy, B. W. J., and Choppin, P. W., 1976, The synthesis of Sendai virus polypeptides in infected cells, Virology 69:116–131.

    PubMed  CAS  Google Scholar 

  • Leppert, M., Rittenhouse, L., Perrault, J., Summers, D. F., and Kolakofsky, D., 1979, Plus-and minus-strand leader RNAs in negative strand virus infected cells, Cell 18:735–747.

    PubMed  CAS  Google Scholar 

  • Martinet, C., Combard, A., Printz-Arne, C., and Printz, P., 1979, Envelope proteins and replication of vesicular stomatitis virus: In vivo effects of RNA+ temperature-sensitive mutations on viral RNA synthesis, J. Virol. 29:123–133.

    PubMed  CAS  Google Scholar 

  • Marx, P. A., Pridgen, C., and Kingsbury, D. W., 1975, Location and abundance of poly(A) sequences in Sendai virus messenger RNA molecules, J. Gen. Virol. 27:247–250.

    PubMed  Google Scholar 

  • Marx, P. A., Portner, A., and Kingsbury, D. W., 1974, Sendai virus transcriptase complex: Polypeptide composition and inhibition by virion envelope proteins, J. Virol. 13:107–112.

    PubMed  CAS  Google Scholar 

  • Morgan, E., and Rakestraw, K., 1986, Sequence of the Sendai L gene: Open reading frames upstream of the main coding region suggest that the gene may be polycistronic, Virology 154:31–40.

    PubMed  CAS  Google Scholar 

  • Morgan, E. M., Re, G. G., and Kingsbury, D. W., 1984, Complete sequence of the Sendai virus NP gene from a cloned insert, Virology 135:279–287.

    PubMed  CAS  Google Scholar 

  • Moyer, S. A., Baker, S. C., and Lessard, J. L., 1986, Tubulin: A factor necessary for the synthesis of both Sendai virus and vesicular stomatitis virus RNAs, Proc. Natl. Acad. Sci. USA 83:5405–5409.

    PubMed  CAS  Google Scholar 

  • Omata-Yamada, T., Hagiwara, K., Katoh, K., Yamada, H., and Iwasaki, K., 1988, Purification of the Sendai virus nonstructural C protein expressed in E. coli, and preparation of antiserum against C protein, Arch. Virol. 103:61–72.

    PubMed  CAS  Google Scholar 

  • Ongradi, J., Cunningham, C., and Szilagyi, J. F., 1985, The role of polypeptides L and NS in the transcription process of vesicular stomatitis virus New Jersey using the temperature sensitive mutant ts El, J. Gen. Virol. 66:1011–1023.

    PubMed  CAS  Google Scholar 

  • Patwardhan, S., and Gupta, D. C., 1988, Translation initiation potential of the 5′ proximal AUGs of the polycistronic P/C mRNA of Sendai virus, J. Biol. Chem. 263:4907–4913.

    PubMed  CAS  Google Scholar 

  • Peluso, R. W., and Moyer, S. A., 1983, Initiation and replication of vesicular stomatitis virus genome RNA in a cell-free system, Proc. Natl. Acad. Sci. USA 80:3198–3202.

    PubMed  CAS  Google Scholar 

  • Peluso, R. W., and Moyer, S. A., 1988, Viral proteins required for the in vitro replication of vesicular stomatitis virus defective interfering particle genome RNA, Virology 162:369–376.

    PubMed  CAS  Google Scholar 

  • Ponstingl, H., Krauhs, E., Little, M., and Kempf, T., 1981, Complete amino acid sequence of alpha-tubulin from porcine brain, Proc. Natl. Acad. Sci. USA 78:2757–2761.

    PubMed  CAS  Google Scholar 

  • Portner, A., 1982, Synthesis of message and genome RNAs in vitro by Sendai virus-infected cell nucleocapsids, J. Gen. Virol. 60:67–75.

    PubMed  CAS  Google Scholar 

  • Portner, A., and Murti, K. G., 1986, Localization of P, NP and M proteins on Sendai virus nucleocapsid using immunogold labeling, Virology 150:469–478.

    PubMed  CAS  Google Scholar 

  • Portner, A., Gupta, K. C., Seyer, J. M., Beachy, E. H., and Kingsbury, D. W., 1986, Localization and characterization of Sendai virus nonstructural C and C′ atproteins by antibodies against synthetic peptides, Virus Res. 6:109–121.

    PubMed  CAS  Google Scholar 

  • Portner, A., Murti, K. G., Morgan, E. M., and Kingsbury, D. W., 1988, Antibodies against Sendai virus L protein: Distribution of the protein in nucleocapsids revealed by immunoelectron microscopy, Virology 163:236–239.

    PubMed  CAS  Google Scholar 

  • Pridgen, C., and Kingsbury, D. W., 1972, Adenylate-rich sequences in Sendai virus transcripts from infected cells, J. Virol. 10:314–317.

    PubMed  CAS  Google Scholar 

  • Ray, J., and Fujinami, R. S., 1987, Characterization of in vitro transcription and transcriptional products of measles virus, J. Virol. 61:3381–3387.

    PubMed  CAS  Google Scholar 

  • Richardson, C. D., Berkovich, A., Rozenblatt, S., and Bellini, W. J., 1985, Use of antibodies directed against synthetic peptides for identifying cDNA clones, establishing reading frames and deducing the gene order of measles virus, J. Virol. 54:186–193.

    PubMed  CAS  Google Scholar 

  • Richardson, C., Hull, D., Greer, P., Hasel, K., Berkovich, A., Englund, G., Bellini, W., Rima, B., and Lazzarini, R., 1986, The nucleotide sequence of the mRNA encoding the fusion protein of measles virus (Edmonston strain): A comparison of fusion proteins from several different paramyxoviruses, Virology 155:508–523.

    PubMed  CAS  Google Scholar 

  • Rima, B. K., Baczko, K., Clarke, D. K., Curran, M. D., Marten, S. J., Billeter, M. A., and ter Meulen, V., 1986, Characterization of clones for the sixth (I) gene and a transcriptional map for morbilliviruses, J. Gen. Virol. 67:1971–1978.

    PubMed  CAS  Google Scholar 

  • Robinson, W. S., 1971a, Ribonucleic acid polymerase in Sendai virions and nucleocapsids, J. Virol. 8:81–86.

    PubMed  CAS  Google Scholar 

  • Robinson, W. S., 1971b, Sendai virus RNA synthesis and nucleocapsid formation in the presence of cyclohexamide, Virology 44:494–502.

    PubMed  CAS  Google Scholar 

  • Rozenblatt, S., Eizenberg, O., Ben-Levy, R., Lavie, V, and Bellini, W. J., 1985, Sequence homology with the morbilliviruses, J. Virol. 53:684–690.

    PubMed  CAS  Google Scholar 

  • Ryan, K. W., and Kingsbury, D. W., 1988, Carboxyl-terminal region of Sendai virus P protein is required for binding to viral nucleocapsids, Virology 167:106–112.

    PubMed  CAS  Google Scholar 

  • Seifried, A. S., Albrecht, P., and Melstien, J. B., 1978, Characterization of an RNA-dependent RNA polymerase activity associated with measles virus, J. Virol. 25:781–787.

    PubMed  CAS  Google Scholar 

  • Shioda, T., Hidaka, Y., Kanda, T., Shibuta, H., Nomoto, A. and Iwasaki, K., 1983, Sequence of 3687 nucleotides from the 3′ end of Sendai virus genome RNA and the predicted amino acid sequences of viral NP, P and C proteins, Nucleic Acid Res. 11:7317–7330.

    PubMed  CAS  Google Scholar 

  • Shioda, T., Iwasaki, K., and Shibuta, H., 1986, Determination of the complete nucleotide sequence of the Sendai virus genome RNA and the predicted amino acid sequences of the F, HN and L proteins, Nucleic Acid Res. 14:1545–1563.

    PubMed  CAS  Google Scholar 

  • Shubert, M., Harmison, G. G., and Meier, E., 1984, Primary structure of the vesicular stomatitis virus polymerases (L) gene: Evidence for a high frequency of mutations, J. Virol. 51:505–514.

    Google Scholar 

  • Stallcup, K. C., Raine, C. S., and Fields, B. N., 1983, Cytochalasin B inhibits the maturation of measles virus, Virology 124:59–74.

    PubMed  CAS  Google Scholar 

  • Stone, H. O., and Kingsbury, D. W., 1973, Stimulation of Sendai virion transcriptase by polyanions, J. Virol. 11:243–249.

    PubMed  CAS  Google Scholar 

  • Stone, H. O., Portner, A., and Kingsbury, D. W., 1971, Ribonucleic acid transcriptases in Sendai virions and infected cells, J. Virol. 8:174–180.

    PubMed  CAS  Google Scholar 

  • Taira, H., Kanda, T., Omata, T., Shibuta, H., Kawakita, M., and Iwasaki, K., 1987, Interferon induction by transfection of Sendai virus C gene cDNA, J. Virol. 61:625–628.

    PubMed  CAS  Google Scholar 

  • Thomas, S. M., Lamb, R. A., and Paterson, R. G., 1988, Two mRNAs that differ by two nontemp-lated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5, Cell 54:891–902.

    PubMed  CAS  Google Scholar 

  • Tordo, N., Poch, O., Ermine, A., Keith, G., and Rougeon, F., 1988, Completion of the rabies virus genome sequence determination: Highly conserved domains among the (L) polymerase proteins of unsegmented negative-strand RNA viruses, Virology 165:565–576.

    PubMed  CAS  Google Scholar 

  • Tyrrell, D. L. J., and Norrby, E., 1978, Structural polypeptides of measles virus, J. Gen. Virol. 39:219–229.

    PubMed  CAS  Google Scholar 

  • Vidal, S., and Kolakofsky, D., 1989, Modified model for the switch from Sendai virus transcription to replication, J. Virol. 63:1951–1958.

    PubMed  CAS  Google Scholar 

  • Vidal, S., Curran, J., Orvell, C., and Kolakofsky, D., 1988, Mapping of monoclonal antibodies to the Sendai virus P protein and the location of its phosphates, J. Virol. 62:2200–2203.

    PubMed  CAS  Google Scholar 

  • Wang, E., Wolf, B. A., Lamb, R. A., Choppin, P. W, and Goldberg, R. A., 1976, The presence of actin in enveloped viruses, in “Cell Motility” (R. Goldman, T. Pollard, and J. Rosenbaum, ed.), pp. 589–599, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.

    Google Scholar 

  • Wilde, A., and Morrison, T., 1984, Structural and functional characterization of Newcastle disease virus polycistronic RNA species, J. Virol. 51:71–76.

    PubMed  CAS  Google Scholar 

  • Yoshikawa, Y., Mizumoto, K., and Yamanouchi, K., 1986, Characterization of messenger RNAs of measles virus, J. Gen. Virol. 67:2807–2812.

    PubMed  CAS  Google Scholar 

  • Yusoff, K., Millar, N. S., Chambers, P. and Emmerson, P. T. 1987, Nucleotide sequence analysis of the L gene of Newcastle disease virus: Homologies with Sendai and vesicular stomatitis virus, Nucleic Acids Res. 15:3961–3976.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Immunology and Medical Microbiology, University of Florida College of Medicine, Gainesville, Florida, 32610, USA

    Sue A. Moyer & Sandra M. Horikami

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  1. Sue A. Moyer
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  2. Sandra M. Horikami
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  1. Howard Hughes Medical Institute, Bethesda, Maryland, USA

    David W. Kingsbury

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© 1991 Springer Science+Business Media New York

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Moyer, S.A., Horikami, S.M. (1991). The Role of Viral and Host Cell Proteins in Paramyxovirus Transcription and Replication. In: Kingsbury, D.W. (eds) The Paramyxoviruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3790-8_9

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  • DOI: https://doi.org/10.1007/978-1-4615-3790-8_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6689-8

  • Online ISBN: 978-1-4615-3790-8

  • eBook Packages: Springer Book Archive

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