DNA Topology in Halobacteria

  • Patrick Forterre
  • Daniele Gadelle
  • Franck Charbonnier
  • Mouldy Sioud
Part of the NATO ASI Series book series (NSSA, volume 201)


Inhibitors of eubacterial and eucaryotic DNA topoisomerases II induce topological changes and/or DNA cleavage in the plasmids of halobacteria. As in eubacteria, novobiocin halts DNA replication and induces positive supercoiling of plasmids in halobacteria. This positive supercoiling is prevented by actinomycin D, indicating that it may be generated by transcription as in eubacteria.


Reverse Gyrase Positive Supercoiling Thermophilic Archaebacterium Thermophilic Archae Reverse Gyrase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Patrick Forterre
    • 1
  • Daniele Gadelle
    • 1
  • Franck Charbonnier
    • 1
  • Mouldy Sioud
    • 1
  1. 1.Institut de Génétique et MicrobiologieUniversité Paris-SudOrsay CedexFrance

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