Biochemical Characterization of Dihydrofolate Reductase of Halobacterium Volcanii
The enzymatic activity of the enzyme dihydrofolate reductase of Halobacterium volcanii depends on salt concentration. the following communication describes the effect of salt concentration and pH on the catalytic parameters of this enzyme. In addition, the mode of inhibition of three different inhibitors of DHFR was studied.
KeywordsCatalysis Half Life Methotrexate Folic Acid NADPH
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