As for any other bio-medical measurement, topographic maps are subject to variations, not only among subjects, but even at different times within the same subject. Therefore statistical methods must be employed in order to separate the consistent part of the features of interest from the variability due to extraneous factors. For instance, in order to study and understand the significance of a spike topography, one must be able to identify the salient characteristics of that structure and separate them from minor and irrelevant variations in space, time and magnitude (alpha, muscle artifacts etc.).
KeywordsStatistical Approach Mahalanobis Distance Classification Tree Terminal Node Classification Rule
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