Case-Control Studies on Cancer Risk in G6PD-Deficient Male Populations

  • P. L. Cocco
  • S. Dessi
  • P. Manca
  • R. Cherchi
  • M. Pisano
  • P. F. Todde


Glucose-6-Phosphate Deydrogenase (G6PD) deficiency is a sex-linked hereditary condition which frequently occurs in the populations of the mediterranean area and particularly in Sardinia. The enzyme deficiency is routinely detected in erythrocytes. However, it was also found in several other tissues of G6PD-deficient subjects1,7. In spite of its ubiquity, a possible acute haemolytic crisis following either the alimentary assumption of broad beans or the inhalation of its pollen is the only clinical symptom which is known to be related to G6PD deficiency.


Broad Bean G6PD Deficiency Dehydrogenase Deficiency G6PD Activity Lower Cancer Risk 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • P. L. Cocco
    • 1
  • S. Dessi
    • 2
  • P. Manca
    • 1
  • R. Cherchi
    • 3
  • M. Pisano
    • 3
  • P. F. Todde
    • 4
  1. 1.Istituto di Medicina del LavoroUniversita di CagliariItaly
  2. 2.Istituto di Farmacologia e Patologia Biochimica, Cattedra di Patologia GeneraleUniversita di CagliariItaly
  3. 3.Divisione di Chirurgia ToracicaOspedale BinaghiCagliariItaly
  4. 4.Servizio di Anatomia PatologicaOspedale S MicheleCagliariItaly

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