Chronic Inflammation is a Major Cause of Preventable Cancer
Chronic inflammation from chronic infections or smoking is a major risk factor for cancer. The toxic oxidants released by phagocytes damage DNA directly and, in order to promote wound healing, are also signals for mitogenesis. The inflammation-induced mutagenesis and mitogenesis produce a synergistic response that contributes to cancer. The inflammatory response can be mitigated by antioxidants and other dietary factors.