Osteosarcoma: Experience with the Rosen T10 protocol at RCH, Melbourne

  • Henry Ekert
  • Karin Tiedemann
Part of the Cancer Treatment and Research book series (CTAR, volume 62)


The poor prognosis of children with osteosarcoma treated with amputation alone or with irradiation followed by amputation has been amply confirmed in the literature. In a retrospective survey in our institution carried out over the years 1965–1975, the 3-year survival rate was 5%.


Preoperative Chemotherapy Histologic Response Primary Osteogenic Sarcoma Lower Urine Output Diagnosis Figure 
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    Rosen G, Marcove RC, Caparros B, et al. Primary osteogenic sarcoma: the rationale for preoperative chemotherapy and delayed surgery. Cancer 43:2163–2177, 1979.PubMedCrossRefGoogle Scholar
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    Rosen G, Caparros B, Huvos AG, et al. Preoperative chemotherapy for osteogenic sarcoma: selection of post-operative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer 49:1221–1230, 1982.PubMedCrossRefGoogle Scholar
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    Provisor A, Nachman J, Krailo M, et al. Treatment of non-metastatic osteogenic sarcoma (OS) of the extremities with pre and post-operative chemotherapy. Proc Am Soc Clin Oncol 6:217, abstr 855, 1987.Google Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Henry Ekert
    • 1
  • Karin Tiedemann
    • 1
  1. 1.Royal Children’s Hospital MelbourneVictoriaAustralia

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